Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report

This is a case report of a Gustilo-Anderson Type IIIB comminuted open right tibial fracture with massive bone loss, complicated by methicillin-resistant Staphylococus aureus (MRSA) infection. Non-viable and contaminated bony fragments were removed and infected bone resected. Soft tissue coverage and...

Descripción completa

Detalles Bibliográficos
Autores principales: Saw, KY, Gill, R, Low, TC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Malaysian Orthopaedic Association 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751995/
https://www.ncbi.nlm.nih.gov/pubmed/33403079
http://dx.doi.org/10.5704/MOJ.2011.026
_version_ 1783625765977325568
author Saw, KY
Gill, R
Low, TC
author_facet Saw, KY
Gill, R
Low, TC
author_sort Saw, KY
collection PubMed
description This is a case report of a Gustilo-Anderson Type IIIB comminuted open right tibial fracture with massive bone loss, complicated by methicillin-resistant Staphylococus aureus (MRSA) infection. Non-viable and contaminated bony fragments were removed and infected bone resected. Soft tissue coverage and antibiotics were effective against the MRSA infection. A unifocal bone transport with the Ilizarov method regenerated 13cm of the missing tibia. Autologous peripheral blood stem cells (PBSC) injections into the osteogenesis site boosted bone regeneration and consolidation with a shortened Bone Healing index (BHI) of 23 days/cm.
format Online
Article
Text
id pubmed-7751995
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Malaysian Orthopaedic Association
record_format MEDLINE/PubMed
spelling pubmed-77519952021-01-04 Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report Saw, KY Gill, R Low, TC Malays Orthop J Case Report This is a case report of a Gustilo-Anderson Type IIIB comminuted open right tibial fracture with massive bone loss, complicated by methicillin-resistant Staphylococus aureus (MRSA) infection. Non-viable and contaminated bony fragments were removed and infected bone resected. Soft tissue coverage and antibiotics were effective against the MRSA infection. A unifocal bone transport with the Ilizarov method regenerated 13cm of the missing tibia. Autologous peripheral blood stem cells (PBSC) injections into the osteogenesis site boosted bone regeneration and consolidation with a shortened Bone Healing index (BHI) of 23 days/cm. Malaysian Orthopaedic Association 2020-11 /pmc/articles/PMC7751995/ /pubmed/33403079 http://dx.doi.org/10.5704/MOJ.2011.026 Text en © 2020 Malaysian Orthopaedic Association (MOA). All Rights Reserved http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
spellingShingle Case Report
Saw, KY
Gill, R
Low, TC
Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
title Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
title_full Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
title_fullStr Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
title_full_unstemmed Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
title_short Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case Report
title_sort massive tibial bone regeneration with autologous peripheral blood stem cells using ilizarov bone transport: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751995/
https://www.ncbi.nlm.nih.gov/pubmed/33403079
http://dx.doi.org/10.5704/MOJ.2011.026
work_keys_str_mv AT sawky massivetibialboneregenerationwithautologousperipheralbloodstemcellsusingilizarovbonetransportacasereport
AT gillr massivetibialboneregenerationwithautologousperipheralbloodstemcellsusingilizarovbonetransportacasereport
AT lowtc massivetibialboneregenerationwithautologousperipheralbloodstemcellsusingilizarovbonetransportacasereport

Ejemplares similares