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Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications

OBJECTIVES: To perform a radio‐anatomical evaluation of the nasal cavity floor free mucosal graft (endonasal extended mucoplasty, EEM) to repair mucosal defects after an extended ethmoid‐sphenoidotomy. METHODS: A human cadaveric study (radiological and anatomical dissection) and an in vivo study in...

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Autores principales: González‐García, Jaime, Moreno‐Luna, Ramón, Palacios‐García, José, Del Cuvillo Bernal, Alfonso, Maza‐Solano, Juan M., Santos Pérez, Jaime, Pinheiro‐Neto, Carlos D., Sánchez‐Gómez, Serafín, Ambrosiani Fernández, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752033/
https://www.ncbi.nlm.nih.gov/pubmed/33364389
http://dx.doi.org/10.1002/lio2.503
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author González‐García, Jaime
Moreno‐Luna, Ramón
Palacios‐García, José
Del Cuvillo Bernal, Alfonso
Maza‐Solano, Juan M.
Santos Pérez, Jaime
Pinheiro‐Neto, Carlos D.
Sánchez‐Gómez, Serafín
Ambrosiani Fernández, Jesús
author_facet González‐García, Jaime
Moreno‐Luna, Ramón
Palacios‐García, José
Del Cuvillo Bernal, Alfonso
Maza‐Solano, Juan M.
Santos Pérez, Jaime
Pinheiro‐Neto, Carlos D.
Sánchez‐Gómez, Serafín
Ambrosiani Fernández, Jesús
author_sort González‐García, Jaime
collection PubMed
description OBJECTIVES: To perform a radio‐anatomical evaluation of the nasal cavity floor free mucosal graft (endonasal extended mucoplasty, EEM) to repair mucosal defects after an extended ethmoid‐sphenoidotomy. METHODS: A human cadaveric study (radiological and anatomical dissection) and an in vivo study in surgical patients with CRSwNP were performed. The EEM areas were compared between 3D reconstruction from CT scans and anatomical/surgical dissections, both in cadaver specimens and in patients. Feasibility was assessed by correlation between the EEM area on CT scans and when harvested in cadavers and when grafted in patients. Usefulness was assessed by the degree of coverage of the EEM in the surface exposed after an extended ethmoid‐sphenoidotomy. Both feasibility and usefulness were assessed in cadaveric specimens (n = 15) and patients (n = 4). RESULTS: Fifteen cadaveric specimens and 4 patients with bilateral CRSwNP were included. The mean (SD) areas obtained in the cadaveric radiological and anatomical studies were 9.44 (2.07) cm(2) and 8.03 (1.36) cm(2), respectively (intraclass correlation coefficient 0.59, moderate correlation), and in 3D reconstruction for operated patients were 10.32 (0.98) cm(2) and 11.27 (2.44) cm(2), respectively. The coverage of the ethmoidal roof in the cadaveric dissection study was 100%, from the anterior ethmoidal artery to the posterior ethmoidal artery, covering the planun sphenoidale up to 75% in the case series. In 87.5% of the cases, up to 50% of the papiracea lamina was covered. CONCLUSION: The EEM have shown to be a feasible and useful grafting technique to repair skull base defects after performing an extended ethmoid‐sphenoidotomy during surgery for CRSwNP. LEVEL OF EVIDENCE: NA.
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spelling pubmed-77520332020-12-23 Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications González‐García, Jaime Moreno‐Luna, Ramón Palacios‐García, José Del Cuvillo Bernal, Alfonso Maza‐Solano, Juan M. Santos Pérez, Jaime Pinheiro‐Neto, Carlos D. Sánchez‐Gómez, Serafín Ambrosiani Fernández, Jesús Laryngoscope Investig Otolaryngol Allergy, Rhinology, and Immunology OBJECTIVES: To perform a radio‐anatomical evaluation of the nasal cavity floor free mucosal graft (endonasal extended mucoplasty, EEM) to repair mucosal defects after an extended ethmoid‐sphenoidotomy. METHODS: A human cadaveric study (radiological and anatomical dissection) and an in vivo study in surgical patients with CRSwNP were performed. The EEM areas were compared between 3D reconstruction from CT scans and anatomical/surgical dissections, both in cadaver specimens and in patients. Feasibility was assessed by correlation between the EEM area on CT scans and when harvested in cadavers and when grafted in patients. Usefulness was assessed by the degree of coverage of the EEM in the surface exposed after an extended ethmoid‐sphenoidotomy. Both feasibility and usefulness were assessed in cadaveric specimens (n = 15) and patients (n = 4). RESULTS: Fifteen cadaveric specimens and 4 patients with bilateral CRSwNP were included. The mean (SD) areas obtained in the cadaveric radiological and anatomical studies were 9.44 (2.07) cm(2) and 8.03 (1.36) cm(2), respectively (intraclass correlation coefficient 0.59, moderate correlation), and in 3D reconstruction for operated patients were 10.32 (0.98) cm(2) and 11.27 (2.44) cm(2), respectively. The coverage of the ethmoidal roof in the cadaveric dissection study was 100%, from the anterior ethmoidal artery to the posterior ethmoidal artery, covering the planun sphenoidale up to 75% in the case series. In 87.5% of the cases, up to 50% of the papiracea lamina was covered. CONCLUSION: The EEM have shown to be a feasible and useful grafting technique to repair skull base defects after performing an extended ethmoid‐sphenoidotomy during surgery for CRSwNP. LEVEL OF EVIDENCE: NA. John Wiley & Sons, Inc. 2020-11-18 /pmc/articles/PMC7752033/ /pubmed/33364389 http://dx.doi.org/10.1002/lio2.503 Text en © 2020 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Allergy, Rhinology, and Immunology
González‐García, Jaime
Moreno‐Luna, Ramón
Palacios‐García, José
Del Cuvillo Bernal, Alfonso
Maza‐Solano, Juan M.
Santos Pérez, Jaime
Pinheiro‐Neto, Carlos D.
Sánchez‐Gómez, Serafín
Ambrosiani Fernández, Jesús
Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
title Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
title_full Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
title_fullStr Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
title_full_unstemmed Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
title_short Radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
title_sort radioanatomical study of the extended free nasal floor mucosal graft and its clinical applications
topic Allergy, Rhinology, and Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752033/
https://www.ncbi.nlm.nih.gov/pubmed/33364389
http://dx.doi.org/10.1002/lio2.503
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