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Turning the Mre11/Rad50 DNA repair complex on its head: lessons from SMC protein hinges, dynamic coiled-coil movements and DNA loop-extrusion?

The bacterial SbcC/SbcD DNA repair proteins were identified over a quarter of a century ago. Following the subsequent identification of the homologous Mre11/Rad50 complex in the eukaryotes and archaea, it has become clear that this conserved chromosomal processing machinery is central to DNA repair...

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Detalles Bibliográficos
Autores principales:	Zabolotnaya, Ekaterina, Mela, Ioanna, Henderson, Robert M., Robinson, Nicholas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752040/ https://www.ncbi.nlm.nih.gov/pubmed/33300987 http://dx.doi.org/10.1042/BST20170168

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