Cargando…

Emerging nanomaterials for dental treatments

The emergence of nanomaterials for dental treatments is encouraged by the nanotopography of the tooth structure, together with the promising benefits of nanomedicine. The use of nanoparticles in dentistry, also termed as ‘nanodentistry', has manifested in applications for remineralisation, anti...

Descripción completa

Detalles Bibliográficos
Autores principales: Mok, Zi Hong, Proctor, Gordon, Thanou, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752085/
https://www.ncbi.nlm.nih.gov/pubmed/33200780
http://dx.doi.org/10.1042/ETLS20200195
_version_ 1783625787158560768
author Mok, Zi Hong
Proctor, Gordon
Thanou, Maya
author_facet Mok, Zi Hong
Proctor, Gordon
Thanou, Maya
author_sort Mok, Zi Hong
collection PubMed
description The emergence of nanomaterials for dental treatments is encouraged by the nanotopography of the tooth structure, together with the promising benefits of nanomedicine. The use of nanoparticles in dentistry, also termed as ‘nanodentistry', has manifested in applications for remineralisation, antimicrobial activity, local anaesthesia, anti-inflammation, osteoconductivity and stem cell differentiation. Besides the applications on dental tissues, nanoparticles have been used to enhance the mechanical properties of dental composites, improving their bonding and anchorage and reducing friction. The small particle size allows for enhanced permeation into deeper lesions, and reduction in porosities of dental composites for higher mechanical strength. The large surface area to volume ratio allows for enhanced bioactivity such as bonding and integration, and more intense action towards microorganisms. Controlled release of encapsulated bioactive molecules such as drugs and growth factors enables them to be delivered more precisely, with site-targeted delivery for localised treatments. These properties have benefitted across multiple fields within dentistry, including periodontology and endodontics and reengineering of dental prosthetics and braces. This review summarises the current literature on the emerging field of nanomaterials for dental treatments.
format Online
Article
Text
id pubmed-7752085
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Portland Press Ltd.
record_format MEDLINE/PubMed
spelling pubmed-77520852021-01-05 Emerging nanomaterials for dental treatments Mok, Zi Hong Proctor, Gordon Thanou, Maya Emerg Top Life Sci Review Articles The emergence of nanomaterials for dental treatments is encouraged by the nanotopography of the tooth structure, together with the promising benefits of nanomedicine. The use of nanoparticles in dentistry, also termed as ‘nanodentistry', has manifested in applications for remineralisation, antimicrobial activity, local anaesthesia, anti-inflammation, osteoconductivity and stem cell differentiation. Besides the applications on dental tissues, nanoparticles have been used to enhance the mechanical properties of dental composites, improving their bonding and anchorage and reducing friction. The small particle size allows for enhanced permeation into deeper lesions, and reduction in porosities of dental composites for higher mechanical strength. The large surface area to volume ratio allows for enhanced bioactivity such as bonding and integration, and more intense action towards microorganisms. Controlled release of encapsulated bioactive molecules such as drugs and growth factors enables them to be delivered more precisely, with site-targeted delivery for localised treatments. These properties have benefitted across multiple fields within dentistry, including periodontology and endodontics and reengineering of dental prosthetics and braces. This review summarises the current literature on the emerging field of nanomaterials for dental treatments. Portland Press Ltd. 2020-12-17 2020-11-17 /pmc/articles/PMC7752085/ /pubmed/33200780 http://dx.doi.org/10.1042/ETLS20200195 Text en © 2020 The Author(s) https://creativecommons.org/licenses/by/4.0/ This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and the Royal Society of Biology and distributed under the Creative Commons Attribution License 4.0 (CC BY) (https://creativecommons.org/licenses/by/4.0/) . Open access for this article was enabled by the participation of King's College London in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC.
spellingShingle Review Articles
Mok, Zi Hong
Proctor, Gordon
Thanou, Maya
Emerging nanomaterials for dental treatments
title Emerging nanomaterials for dental treatments
title_full Emerging nanomaterials for dental treatments
title_fullStr Emerging nanomaterials for dental treatments
title_full_unstemmed Emerging nanomaterials for dental treatments
title_short Emerging nanomaterials for dental treatments
title_sort emerging nanomaterials for dental treatments
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752085/
https://www.ncbi.nlm.nih.gov/pubmed/33200780
http://dx.doi.org/10.1042/ETLS20200195
work_keys_str_mv AT mokzihong emergingnanomaterialsfordentaltreatments
AT proctorgordon emergingnanomaterialsfordentaltreatments
AT thanoumaya emergingnanomaterialsfordentaltreatments