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Exploiting codon usage identifies intensity-specific modifiers of Ras/MAPK signaling in vivo
Signal transduction pathways are intricately fine-tuned to accomplish diverse biological processes. An example is the conserved Ras/mitogen-activated-protein-kinase (MAPK) pathway, which exhibits context-dependent signaling output dynamics and regulation. Here, by altering codon usage as a novel pla...
Autores principales: | Sawyer, Jessica K., Kabiri, Zahra, Montague, Ruth A., Allen, Scott R., Stewart, Rebeccah, Paramore, Sarah V., Cohen, Erez, Zaribafzadeh, Hamed, Counter, Christopher M., Fox, Donald T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752094/ https://www.ncbi.nlm.nih.gov/pubmed/33296356 http://dx.doi.org/10.1371/journal.pgen.1009228 |
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