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Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019
Scabies is an important predisposing factor for impetigo but its role in more serious skin and soft tissue infections (SSTIs) is not well understood. Information is limited on incidence of SSTIs in the presence of endemic scabies. We conducted a prospective study of hospital admissions for SSTIs in...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752096/ https://www.ncbi.nlm.nih.gov/pubmed/33296378 http://dx.doi.org/10.1371/journal.pntd.0008887 |
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author | Thean, Li Jun Jenney, Adam Engelman, Daniel Romani, Lucia Wand, Handan Mudaliar, Jyotishna Paka, Jessica Cua, Tuliana Taole, Sera Sahukhan, Aalisha Kama, Mike Tuicakau, Meciusela Kado, Joseph Carvalho, Natalie Whitfeld, Margot Kaldor, John Steer, Andrew C. |
author_facet | Thean, Li Jun Jenney, Adam Engelman, Daniel Romani, Lucia Wand, Handan Mudaliar, Jyotishna Paka, Jessica Cua, Tuliana Taole, Sera Sahukhan, Aalisha Kama, Mike Tuicakau, Meciusela Kado, Joseph Carvalho, Natalie Whitfeld, Margot Kaldor, John Steer, Andrew C. |
author_sort | Thean, Li Jun |
collection | PubMed |
description | Scabies is an important predisposing factor for impetigo but its role in more serious skin and soft tissue infections (SSTIs) is not well understood. Information is limited on incidence of SSTIs in the presence of endemic scabies. We conducted a prospective study of hospital admissions for SSTIs in the Northern Division of Fiji (population: 131,914). Prospective surveillance for admissions with impetigo, abscess, cellulitis, wound infection, pyomyositis, necrotizing fasciitis, infected scabies, and crusted scabies was conducted at the Division’s referral hospital between 2018 to 2019. Information was collected on demographic characteristics, clinical features, microbiology, treatment and outcomes. Over the study period, 788 SSTI admissions were recorded corresponding to a population incidence 647 per 100,000 person-years (95%CI 571–660). Incidence was highest at the extremes of age with peak incidence in children aged <5 years (908 per 100,000) and those aged ≥65 years (1127 per 100,000). Incidence was 1.7 times higher among the Indigenous Fijian population (753 per 100,000) compared to other ethnicities (442 per 100,000). Overall case fatality rate was 3.3%, and 10.8% for those aged ≥65 years. Scabies was diagnosed concurrently in 7.6% of all patients and in 24.6% of admitted children <5 years. There is a very high burden of hospital admissions for SSTIs in Fiji compared to high-income settings especially among the youngest, oldest and indigenous population which is concordant with scabies and impetigo distribution in this population. Our findings highlight the need for strategies to reduce the burden of SSTIs in Fiji and similar settings. |
format | Online Article Text |
id | pubmed-7752096 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-77520962021-01-05 Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 Thean, Li Jun Jenney, Adam Engelman, Daniel Romani, Lucia Wand, Handan Mudaliar, Jyotishna Paka, Jessica Cua, Tuliana Taole, Sera Sahukhan, Aalisha Kama, Mike Tuicakau, Meciusela Kado, Joseph Carvalho, Natalie Whitfeld, Margot Kaldor, John Steer, Andrew C. PLoS Negl Trop Dis Research Article Scabies is an important predisposing factor for impetigo but its role in more serious skin and soft tissue infections (SSTIs) is not well understood. Information is limited on incidence of SSTIs in the presence of endemic scabies. We conducted a prospective study of hospital admissions for SSTIs in the Northern Division of Fiji (population: 131,914). Prospective surveillance for admissions with impetigo, abscess, cellulitis, wound infection, pyomyositis, necrotizing fasciitis, infected scabies, and crusted scabies was conducted at the Division’s referral hospital between 2018 to 2019. Information was collected on demographic characteristics, clinical features, microbiology, treatment and outcomes. Over the study period, 788 SSTI admissions were recorded corresponding to a population incidence 647 per 100,000 person-years (95%CI 571–660). Incidence was highest at the extremes of age with peak incidence in children aged <5 years (908 per 100,000) and those aged ≥65 years (1127 per 100,000). Incidence was 1.7 times higher among the Indigenous Fijian population (753 per 100,000) compared to other ethnicities (442 per 100,000). Overall case fatality rate was 3.3%, and 10.8% for those aged ≥65 years. Scabies was diagnosed concurrently in 7.6% of all patients and in 24.6% of admitted children <5 years. There is a very high burden of hospital admissions for SSTIs in Fiji compared to high-income settings especially among the youngest, oldest and indigenous population which is concordant with scabies and impetigo distribution in this population. Our findings highlight the need for strategies to reduce the burden of SSTIs in Fiji and similar settings. Public Library of Science 2020-12-09 /pmc/articles/PMC7752096/ /pubmed/33296378 http://dx.doi.org/10.1371/journal.pntd.0008887 Text en © 2020 Thean et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Thean, Li Jun Jenney, Adam Engelman, Daniel Romani, Lucia Wand, Handan Mudaliar, Jyotishna Paka, Jessica Cua, Tuliana Taole, Sera Sahukhan, Aalisha Kama, Mike Tuicakau, Meciusela Kado, Joseph Carvalho, Natalie Whitfeld, Margot Kaldor, John Steer, Andrew C. Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 |
title | Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 |
title_full | Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 |
title_fullStr | Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 |
title_full_unstemmed | Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 |
title_short | Hospital admissions for skin and soft tissue infections in a population with endemic scabies: A prospective study in Fiji, 2018–2019 |
title_sort | hospital admissions for skin and soft tissue infections in a population with endemic scabies: a prospective study in fiji, 2018–2019 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752096/ https://www.ncbi.nlm.nih.gov/pubmed/33296378 http://dx.doi.org/10.1371/journal.pntd.0008887 |
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