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Conformation of the nuclear pore in living cells is modulated by transport state

While the static structure of the nuclear pore complex (NPC) continues to be refined with cryo-EM and x-ray crystallography, in vivo conformational changes of the NPC remain under-explored. We developed sensors that report on the orientation of NPC components by rigidly conjugating mEGFP to differen...

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Detalles Bibliográficos
Autores principales:	Pulupa, Joan, Prior, Harriet, Johnson, Daniel S, Simon, Sanford M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752133/ https://www.ncbi.nlm.nih.gov/pubmed/33346731 http://dx.doi.org/10.7554/eLife.60654

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