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A computational model of liver tissue damage and repair

Drug induced liver injury (DILI) and cell death can result from oxidative stress in hepatocytes. An initial pattern of centrilobular damage in the APAP model of DILI is amplified by communication from stressed cells and immune system activation. While hepatocyte proliferation counters cell loss, hig...

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Detalles Bibliográficos
Autores principales:	Adhyapok, Priyom, Fu, Xiao, Sluka, James P., Clendenon, Sherry G., Sluka, Victoria D., Wang, Zemin, Dunn, Kenneth, Klaunig, James E., Glazier, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752149/ https://www.ncbi.nlm.nih.gov/pubmed/33347443 http://dx.doi.org/10.1371/journal.pone.0243451

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