Saikosaponin‐d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice

Neural stem/progenitor cells (NPCs) are multipotent stem cells in the central nervous system. Damage to NPCs has been demonstrated to cause adverse effects on neurogenesis and to contribute to neurological diseases. Our previous research suggested that saikosaponin‐d (SSd), a cytostatic drug belongi...

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Detalles Bibliográficos
Autores principales: Qin, Tingting, Yuan, Ziqiao, Yu, Jiayu, Fu, Xinxin, Deng, Xueyang, Fu, Qiang, Ma, Zhanqiang, Ma, Shiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752162/
https://www.ncbi.nlm.nih.gov/pubmed/33377633
http://dx.doi.org/10.1002/ctm2.243

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