Critical effect of Pol escape mutations associated with detrimental allele HLA-C(∗)15:05 on clinical outcome in HIV-1 subtype A/E infection

The mechanism explaining the role of detrimental HLA alleles in HIV-1 infections has been investigated in very few studies. HLA-A∗29:01-B∗07:05-C∗15:05 is a detrimental haplotype in HIV-1 subtype A/E-infected Vietnamese individuals. The accumulation of mutations at Pol 653/657 is associated with a p...

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Detalles Bibliográficos
Autores principales: Murakoshi, Hayato, Chikata, Takayuki, Akahoshi, Tomohiro, Zou, Chengcheng, Borghan, Mohamed Ali, Van Tran, Giang, Nguyen, Trung Vu, Van Nguyen, Kinh, Kuse, Nozomi, Takiguchi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752225/
https://www.ncbi.nlm.nih.gov/pubmed/33031103
http://dx.doi.org/10.1097/QAD.0000000000002704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752225/
https://www.ncbi.nlm.nih.gov/pubmed/33031103
http://dx.doi.org/10.1097/QAD.0000000000002704

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