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Critical effect of Pol escape mutations associated with detrimental allele HLA-C(∗)15:05 on clinical outcome in HIV-1 subtype A/E infection

The mechanism explaining the role of detrimental HLA alleles in HIV-1 infections has been investigated in very few studies. HLA-A∗29:01-B∗07:05-C∗15:05 is a detrimental haplotype in HIV-1 subtype A/E-infected Vietnamese individuals. The accumulation of mutations at Pol 653/657 is associated with a p...

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Detalles Bibliográficos
Autores principales:	Murakoshi, Hayato, Chikata, Takayuki, Akahoshi, Tomohiro, Zou, Chengcheng, Borghan, Mohamed Ali, Van Tran, Giang, Nguyen, Trung Vu, Van Nguyen, Kinh, Kuse, Nozomi, Takiguchi, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752225/ https://www.ncbi.nlm.nih.gov/pubmed/33031103 http://dx.doi.org/10.1097/QAD.0000000000002704

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