Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance

Rod‐like inclusions have rarely been described in cases of monoclonal gammopathy of renal significance or multiple myeloma. The key finding in our case is the strong κ‐light chain positivity of rod‐like inclusions in plasma cells, which confirms their immunoglobulin nature. Therapeutic benefit of bo...

Descripción completa

Detalles Bibliográficos
Autores principales: Okawara, Sayoko, Bando, Kenichiro, Tsukada, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752359/
https://www.ncbi.nlm.nih.gov/pubmed/33364007
http://dx.doi.org/10.1002/ccr3.3362
_version_ 1783625844631011328
author Okawara, Sayoko
Bando, Kenichiro
Tsukada, Junichi
author_facet Okawara, Sayoko
Bando, Kenichiro
Tsukada, Junichi
author_sort Okawara, Sayoko
collection PubMed
description Rod‐like inclusions have rarely been described in cases of monoclonal gammopathy of renal significance or multiple myeloma. The key finding in our case is the strong κ‐light chain positivity of rod‐like inclusions in plasma cells, which confirms their immunoglobulin nature. Therapeutic benefit of bortezomib was also observed.
format Online
Article
Text
id pubmed-7752359
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-77523592020-12-23 Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance Okawara, Sayoko Bando, Kenichiro Tsukada, Junichi Clin Case Rep Clinical Images Rod‐like inclusions have rarely been described in cases of monoclonal gammopathy of renal significance or multiple myeloma. The key finding in our case is the strong κ‐light chain positivity of rod‐like inclusions in plasma cells, which confirms their immunoglobulin nature. Therapeutic benefit of bortezomib was also observed. John Wiley and Sons Inc. 2020-09-21 /pmc/articles/PMC7752359/ /pubmed/33364007 http://dx.doi.org/10.1002/ccr3.3362 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Images
Okawara, Sayoko
Bando, Kenichiro
Tsukada, Junichi
Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
title Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
title_full Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
title_fullStr Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
title_full_unstemmed Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
title_short Light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
title_sort light chain–positive rod‐like inclusions in bone marrow plasma cells associated with monoclonal gammopathy of renal significance
topic Clinical Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752359/
https://www.ncbi.nlm.nih.gov/pubmed/33364007
http://dx.doi.org/10.1002/ccr3.3362
work_keys_str_mv AT okawarasayoko lightchainpositiverodlikeinclusionsinbonemarrowplasmacellsassociatedwithmonoclonalgammopathyofrenalsignificance
AT bandokenichiro lightchainpositiverodlikeinclusionsinbonemarrowplasmacellsassociatedwithmonoclonalgammopathyofrenalsignificance
AT tsukadajunichi lightchainpositiverodlikeinclusionsinbonemarrowplasmacellsassociatedwithmonoclonalgammopathyofrenalsignificance

Ejemplares similares