Extensive amyloid deposits in bone marrow aspirate smears

Amyloid light‐chain (AL) amyloidosis is the most common form of systemic amyloidosis. It can cause progressive organ dysfunction and eventually death, mainly due to cardiac involvement. Amyloidosis may rarely present as extensive amorphous, purplish‐blue deposits in marrow aspirate smears. Demonstra...

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Detalles Bibliográficos
Autores principales: Li, Ting Hon Stanford, Wong, Kit Fai, Wong, Wai Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752360/
https://www.ncbi.nlm.nih.gov/pubmed/33363988
http://dx.doi.org/10.1002/ccr3.3236
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author Li, Ting Hon Stanford
Wong, Kit Fai
Wong, Wai Shan
author_facet Li, Ting Hon Stanford
Wong, Kit Fai
Wong, Wai Shan
author_sort Li, Ting Hon Stanford
collection PubMed
description Amyloid light‐chain (AL) amyloidosis is the most common form of systemic amyloidosis. It can cause progressive organ dysfunction and eventually death, mainly due to cardiac involvement. Amyloidosis may rarely present as extensive amorphous, purplish‐blue deposits in marrow aspirate smears. Demonstration of congophilic property and apple‐green birefringence under polarized light in aspirate smears can allow a rapid diagnosis of amyloidosis.
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spelling pubmed-77523602020-12-23 Extensive amyloid deposits in bone marrow aspirate smears Li, Ting Hon Stanford Wong, Kit Fai Wong, Wai Shan Clin Case Rep Clinical Images Amyloid light‐chain (AL) amyloidosis is the most common form of systemic amyloidosis. It can cause progressive organ dysfunction and eventually death, mainly due to cardiac involvement. Amyloidosis may rarely present as extensive amorphous, purplish‐blue deposits in marrow aspirate smears. Demonstration of congophilic property and apple‐green birefringence under polarized light in aspirate smears can allow a rapid diagnosis of amyloidosis. John Wiley and Sons Inc. 2020-08-30 /pmc/articles/PMC7752360/ /pubmed/33363988 http://dx.doi.org/10.1002/ccr3.3236 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Images
Li, Ting Hon Stanford
Wong, Kit Fai
Wong, Wai Shan
Extensive amyloid deposits in bone marrow aspirate smears
title Extensive amyloid deposits in bone marrow aspirate smears
title_full Extensive amyloid deposits in bone marrow aspirate smears
title_fullStr Extensive amyloid deposits in bone marrow aspirate smears
title_full_unstemmed Extensive amyloid deposits in bone marrow aspirate smears
title_short Extensive amyloid deposits in bone marrow aspirate smears
title_sort extensive amyloid deposits in bone marrow aspirate smears
topic Clinical Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752360/
https://www.ncbi.nlm.nih.gov/pubmed/33363988
http://dx.doi.org/10.1002/ccr3.3236
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