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Overlapping tumor‐specific expression of p53, p16(INK4a), and sirtuin 1 in Bowen's disease: A case report

Understanding the impact of inactivating mutations in SIRT1 on the p53 and p16 tumor suppressor genes may yield new insight into the oncogenic mechanisms underlying Bowen's disease.

Detalles Bibliográficos
Autor principal: Takada, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752376/
https://www.ncbi.nlm.nih.gov/pubmed/33363940
http://dx.doi.org/10.1002/ccr3.3400
Descripción
Sumario:Understanding the impact of inactivating mutations in SIRT1 on the p53 and p16 tumor suppressor genes may yield new insight into the oncogenic mechanisms underlying Bowen's disease.