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CD30‐positive lymphomatous (nonleukemic) variant of adult T‐cell leukemia/lymphoma, HTLV‐1 associated

Nonleukemic variant of HTLV‐1‐associated adult T‐cell leukemia lymphoma (ATLL) is a rare variant, and herein, we describe a case with strong and diffuse positivity of neoplastic cells for CD30. Even though ATLL is aggressive entity with poor prognosis, in our case, there was very good clinical respo...

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Detalles Bibliográficos
Autores principales: Podberezin, Mark, Sohani, Aliyah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752401/
https://www.ncbi.nlm.nih.gov/pubmed/33363748
http://dx.doi.org/10.1002/ccr3.3092
Descripción
Sumario:Nonleukemic variant of HTLV‐1‐associated adult T‐cell leukemia lymphoma (ATLL) is a rare variant, and herein, we describe a case with strong and diffuse positivity of neoplastic cells for CD30. Even though ATLL is aggressive entity with poor prognosis, in our case, there was very good clinical response achieved with brentuximab‐containing regimen. Therefore, HTLV‐1‐associated ATLL can be included in the differential diagnostic approach of CD30‐positive lymphoproliferative disorders.