Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations

This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene.

Detalles Bibliográficos
Autores principales: Nasirnejad Sola, Farzaneh, Morovvati, Saeid, Sabetghadam Moghadam, Mitra, Entezari, Malihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752620/
https://www.ncbi.nlm.nih.gov/pubmed/33363863
http://dx.doi.org/10.1002/ccr3.3294
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author Nasirnejad Sola, Farzaneh
Morovvati, Saeid
Sabetghadam Moghadam, Mitra
Entezari, Malihe
author_facet Nasirnejad Sola, Farzaneh
Morovvati, Saeid
Sabetghadam Moghadam, Mitra
Entezari, Malihe
author_sort Nasirnejad Sola, Farzaneh
collection PubMed
description This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene.
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spelling pubmed-77526202020-12-23 Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations Nasirnejad Sola, Farzaneh Morovvati, Saeid Sabetghadam Moghadam, Mitra Entezari, Malihe Clin Case Rep Case Reports This investigation facilitates a better understanding of inhibitor development, the critical treatment morbidity in HA patients. Furthermore, six novel mutations are reported, which would expand the mutation spectrum of the F8 gene. John Wiley and Sons Inc. 2020-09-15 /pmc/articles/PMC7752620/ /pubmed/33363863 http://dx.doi.org/10.1002/ccr3.3294 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Nasirnejad Sola, Farzaneh
Morovvati, Saeid
Sabetghadam Moghadam, Mitra
Entezari, Malihe
Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
title Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
title_full Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
title_fullStr Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
title_full_unstemmed Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
title_short Mutation detection and inhibitor risk in Iranian patients with Hemophilia A: Six novel mutations
title_sort mutation detection and inhibitor risk in iranian patients with hemophilia a: six novel mutations
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752620/
https://www.ncbi.nlm.nih.gov/pubmed/33363863
http://dx.doi.org/10.1002/ccr3.3294
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AT sabetghadammoghadammitra mutationdetectionandinhibitorriskiniranianpatientswithhemophiliaasixnovelmutations
AT entezarimalihe mutationdetectionandinhibitorriskiniranianpatientswithhemophiliaasixnovelmutations

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