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Systemic sclerosis with renal crisis and pericardial effusion

Scleroderma renal crisis occurs in 10% of patients with systemic sclerosis carrying a poor prognosis. A kidney biopsy is consistent with thrombotic microangiopathy (TMA) with clinical findings discerning it from other TMAs. Progression to ESRD occurs in 50% of patients which can lead to further comp...

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Detalles Bibliográficos
Autores principales: Prudhvi, Kalyan, Jonnadula, Jayasree, Kutti Sridharan, Gurusaravanan, Dominguez, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752628/
https://www.ncbi.nlm.nih.gov/pubmed/33364023
http://dx.doi.org/10.1002/ccr3.3467
Descripción
Sumario:Scleroderma renal crisis occurs in 10% of patients with systemic sclerosis carrying a poor prognosis. A kidney biopsy is consistent with thrombotic microangiopathy (TMA) with clinical findings discerning it from other TMAs. Progression to ESRD occurs in 50% of patients which can lead to further complications necessitating emergent interventions including dialysis. Patients with scleroderma can have pericardial involvement with tamponade physiology requiring intervention such as pericardiocentesis.