Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related

Breast cancer metastasis to the stomach is rare; invasive lobular carcinoma has a predilection to spread to the gastrointestinal system and is morphologically similar to primary diffuse gastric carcinoma. This case highlights heterogeneous metastatic progression and that documentation of heterogenei...

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Detalles Bibliográficos
Autores principales: Kutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Jayanthan, Janani, Da Silva, Leonard, Simpson, Peter T., Lakhani, Sunil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752647/
https://www.ncbi.nlm.nih.gov/pubmed/33363813
http://dx.doi.org/10.1002/ccr3.3257
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author Kutasovic, Jamie R.
McCart Reed, Amy E.
Sokolova, Anna
Jayanthan, Janani
Da Silva, Leonard
Simpson, Peter T.
Lakhani, Sunil R.
author_facet Kutasovic, Jamie R.
McCart Reed, Amy E.
Sokolova, Anna
Jayanthan, Janani
Da Silva, Leonard
Simpson, Peter T.
Lakhani, Sunil R.
author_sort Kutasovic, Jamie R.
collection PubMed
description Breast cancer metastasis to the stomach is rare; invasive lobular carcinoma has a predilection to spread to the gastrointestinal system and is morphologically similar to primary diffuse gastric carcinoma. This case highlights heterogeneous metastatic progression and that documentation of heterogeneity is important for informing future treatment strategies and prognostication.
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spelling pubmed-77526472020-12-23 Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related Kutasovic, Jamie R. McCart Reed, Amy E. Sokolova, Anna Jayanthan, Janani Da Silva, Leonard Simpson, Peter T. Lakhani, Sunil R. Clin Case Rep Case Reports Breast cancer metastasis to the stomach is rare; invasive lobular carcinoma has a predilection to spread to the gastrointestinal system and is morphologically similar to primary diffuse gastric carcinoma. This case highlights heterogeneous metastatic progression and that documentation of heterogeneity is important for informing future treatment strategies and prognostication. John Wiley and Sons Inc. 2020-08-27 /pmc/articles/PMC7752647/ /pubmed/33363813 http://dx.doi.org/10.1002/ccr3.3257 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Kutasovic, Jamie R.
McCart Reed, Amy E.
Sokolova, Anna
Jayanthan, Janani
Da Silva, Leonard
Simpson, Peter T.
Lakhani, Sunil R.
Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
title Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
title_full Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
title_fullStr Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
title_full_unstemmed Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
title_short Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related
title_sort phenotypic drift in metastatic progression of breast cancer: a case report with histologically heterogeneous lesions that are clonally related
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752647/
https://www.ncbi.nlm.nih.gov/pubmed/33363813
http://dx.doi.org/10.1002/ccr3.3257
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