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Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review
Acute pancreatitis (AP), an inflammatory disease of the pancreas, is clinically classified into mild AP, moderately severe, and severe based on local complications and presence of organ failure. Histoplasmosis, caused by the dimorphic fungus Histoplasma capsulatum, typically presents with pulmonary...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752742/ https://www.ncbi.nlm.nih.gov/pubmed/33364138 http://dx.doi.org/10.7759/cureus.12168 |
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author | Asif, Abuzar A Roy, Moni Ahmad, Sharjeel |
author_facet | Asif, Abuzar A Roy, Moni Ahmad, Sharjeel |
author_sort | Asif, Abuzar A |
collection | PubMed |
description | Acute pancreatitis (AP), an inflammatory disease of the pancreas, is clinically classified into mild AP, moderately severe, and severe based on local complications and presence of organ failure. Histoplasmosis, caused by the dimorphic fungus Histoplasma capsulatum, typically presents with pulmonary disease. Extrapulmonary disease/disseminated histoplasmosis can affect the gastrointestinal tract, with only a few reported cases of pancreatitis secondary to the above. We describe a rare case of a young woman who presented with necrotizing pancreatitis secondary to histoplasmosis. The etiology of pancreatitis remained unclear throughout her hospital stay despite extensive workup performed. Diagnosis of disseminated histoplasmosis was based on autopsy findings. |
format | Online Article Text |
id | pubmed-7752742 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-77527422020-12-23 Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review Asif, Abuzar A Roy, Moni Ahmad, Sharjeel Cureus Pathology Acute pancreatitis (AP), an inflammatory disease of the pancreas, is clinically classified into mild AP, moderately severe, and severe based on local complications and presence of organ failure. Histoplasmosis, caused by the dimorphic fungus Histoplasma capsulatum, typically presents with pulmonary disease. Extrapulmonary disease/disseminated histoplasmosis can affect the gastrointestinal tract, with only a few reported cases of pancreatitis secondary to the above. We describe a rare case of a young woman who presented with necrotizing pancreatitis secondary to histoplasmosis. The etiology of pancreatitis remained unclear throughout her hospital stay despite extensive workup performed. Diagnosis of disseminated histoplasmosis was based on autopsy findings. Cureus 2020-12-19 /pmc/articles/PMC7752742/ /pubmed/33364138 http://dx.doi.org/10.7759/cureus.12168 Text en Copyright © 2020, Asif et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Asif, Abuzar A Roy, Moni Ahmad, Sharjeel Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review |
title | Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review |
title_full | Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review |
title_fullStr | Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review |
title_full_unstemmed | Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review |
title_short | Fulminant Pancreatitis Due to Disseminated Histoplasmosis: Case Report and Literature Review |
title_sort | fulminant pancreatitis due to disseminated histoplasmosis: case report and literature review |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752742/ https://www.ncbi.nlm.nih.gov/pubmed/33364138 http://dx.doi.org/10.7759/cureus.12168 |
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