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Engineering the Erythromycin-Producing Strain Saccharopolyspora erythraea HOE107 for the Heterologous Production of Polyketide Antibiotics
Bacteria of the genus Saccharopolyspora produce important polyketide antibiotics, including erythromycin A (Sac. erythraea) and spinosad (Sac. spinosa). We herein report the development of an industrial erythromycin-producing strain, Sac. erythraea HOE107, into a host for the heterologous expression...
Autores principales: | Lü, Jin, Long, Qingshan, Zhao, Zhilong, Chen, Lu, He, Weijun, Hong, Jiali, Liu, Kai, Wang, Yemin, Pang, Xiuhua, Deng, Zixin, Tao, Meifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752772/ https://www.ncbi.nlm.nih.gov/pubmed/33363524 http://dx.doi.org/10.3389/fmicb.2020.593217 |
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