Cargando…

Cathepsin L in COVID-19: From Pharmacological Evidences to Genetics

The coronavirus disease 2019 (COVID-19) pandemics is a challenge without precedent for the modern science. Acute Respiratory Discomfort Syndrome (ARDS) is the most common immunopathological event in SARS-CoV-2, SARS-CoV, and MERS-CoV infections. Fast lung deterioration results of cytokine storm dete...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gomes, Caio P., Fernandes, Danilo E., Casimiro, Fernanda, da Mata, Gustavo F., Passos, Michelle T., Varela, Patricia, Mastroianni-Kirsztajn, Gianna, Pesquero, João Bosco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753008/ https://www.ncbi.nlm.nih.gov/pubmed/33364201 http://dx.doi.org/10.3389/fcimb.2020.589505

Ejemplares similares

Familial Focal Segmental Glomerulosclerosis With Late-Onset Presentation and R229Q/R291W Podocin Mutations
por: Riguetti, Michelle T. P., et al.
Publicado: (2020)

Cathepsins in Bacteria-Macrophage Interaction: Defenders or Victims of Circumstance?
por: Szulc-Dąbrowska, Lidia, et al.
Publicado: (2020)

Inflammation and kidney involvement in human viral diseases caused by SARS-CoV-2, HIV, HCV and HBV
por: da Mata, Gustavo Ferreira, et al.
Publicado: (2021)

Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystatin
por: Dvořáková, Hana, et al.
Publicado: (2020)

Diversity of Hybrid- and Hetero-Pathogenic Escherichia coli and Their Potential Implication in More Severe Diseases
por: Santos, Ana Carolina de Mello, et al.
Publicado: (2020)

Pre-exposure prophylaxis during the SARS-CoV-2 pandemic: can PrEP prevent COVID-19-related symptoms?
por: Fernandes, Danilo Euclides, et al.
Publicado: (2020)

The first appointment with a nephrologist: Brazilian patients’ demographic and kidney function characteristics. A retrospective study
por: Samaan, Farid, et al.
Publicado: (2022)

E-NTPDases: Possible Roles on Host-Parasite Interactions and Therapeutic Opportunities
por: Paes-Vieira, Lisvane, et al.
Publicado: (2021)

Effects of COVID-19 Non-Pharmacological Interventions on Dengue Infection: A Systematic Review and Meta-Analysis
por: Wu, Qin, et al.
Publicado: (2022)

Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitize Bacteria to Antibiotic Treatment
por: Kosgodage, Uchini S., et al.
Publicado: (2019)

Negative correlation between ACE2 gene expression levels and loss of taste in a cohort of COVID-19 hospitalized patients: New clues to long-term cognitive disorders
por: Braga-Paz, Isabela, et al.
Publicado: (2022)

Attenuation of Listeria monocytogenes Virulence by Cannabis sativa L. Essential Oil
por: Marini, Emanuela, et al.
Publicado: (2018)

Molecular mechanisms of Huanglian Jiedu decoction in treating Alzheimer’s disease by regulating microbiome via network pharmacology and molecular docking analysis
por: Zheng, Renyuan, et al.
Publicado: (2023)

Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches
por: Rebello, Karina M., et al.
Publicado: (2019)

Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles
por: Kosgodage, Uchini S., et al.
Publicado: (2019)

Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis
por: Romanelli, Maiara Maria, et al.
Publicado: (2019)

Biological effects of trans, trans-farnesol in Leishmania amazonensis
por: Pinheiro, Liliane Sena, et al.
Publicado: (2023)

A Pilot Randomized Clinical Trial: Oral Miltefosine and Pentavalent Antimonials Associated With Pentoxifylline for the Treatment of American Tegumentary Leishmaniasis
por: Martins, Sofia Sales, et al.
Publicado: (2021)

Iohexol Clearance for Determination of Glomerular Filtration Rate in Rats Induced to Acute Renal Failure
por: Passos, Michelle T., et al.
Publicado: (2015)

Pharmacological Targeting of BMP6-SMAD Mediated Hepcidin Expression Does Not Improve the Outcome of Systemic Infections With Intra-Or Extracellular Gram-Negative Bacteria in Mice
por: Hoffmann, Alexander, et al.
Publicado: (2021)

A systematic study of traditional Chinese medicine treating hepatitis B virus-related hepatocellular carcinoma based on target-driven reverse network pharmacology
por: Yin, Xiaofeng, et al.
Publicado: (2022)

G Protein-Coupled Receptors as Potential Intercellular Communication Mediators in Trypanosomatidae
por: Díaz, Emilia, et al.
Publicado: (2022)

A Search for Novel Legionella pneumophila Effector Proteins Reveals a Strain Specific Nucleotropic Effector
por: Monteiro, Inês P., et al.
Publicado: (2022)

The Type III Secretion Effector CteG Mediates Host Cell Lytic Exit of Chlamydia trachomatis
por: Pereira, Inês Serrano, et al.
Publicado: (2022)

Genetic and Functional Characterization of Toll-Like Receptor Responses in Immunocompetent Patients With CMV Mononucleosis
por: Frascaroli, Giada, et al.
Publicado: (2020)

The antigen processing-associated transporter gene polymorphism: Role on gene and protein expression in HPV-infected pre-cancerous cervical lesion
por: Medeiros, Fernanda Silva, et al.
Publicado: (2022)

Genetic and Virulence Characteristics of a Hybrid Atypical Enteropathogenic and Uropathogenic Escherichia coli (aEPEC/UPEC) Strain
por: Valiatti, Tiago B., et al.
Publicado: (2020)

Tracing Back the Evolutionary Route of Enteroinvasive Escherichia coli (EIEC) and Shigella Through the Example of the Highly Pathogenic O96:H19 EIEC Clone
por: Michelacci, Valeria, et al.
Publicado: (2020)

The epitranscriptome of Vero cells infected with SARS-CoV-2 assessed by direct RNA sequencing reveals m6A pattern changes and DRACH motif biases in viral and cellular RNAs
por: Campos, João H. C., et al.
Publicado: (2022)

Thymic Microenvironment Is Modified by Malnutrition and Leishmania infantum Infection
por: Losada-Barragán, Monica, et al.
Publicado: (2019)

Meglumine antimoniate was associated with a higher cure rate than liposomal amphotericin B in the treatment of American tegumentary leishmaniasis: A retrospective cohort study from a Leishmania braziliensis-endemic area
por: Barroso, Daniel Holanda, et al.
Publicado: (2022)

Functional Polymorphisms in the p53 Pathway Genes on the Genetic Susceptibility to Zika Virus Teratogenesis
por: Gomes, Julia A., et al.
Publicado: (2021)

Integrative and Conjugative Elements of Helicobacter pylori Are Hypothetical Virulence Factors Associated With Gastric Cancer
por: Mucito-Varela, Eduardo, et al.
Publicado: (2020)

Genomic Properties and Temporal Analysis of the Interaction of an Invasive Escherichia albertii With Epithelial Cells
por: Romão, Fabiano T., et al.
Publicado: (2020)

The Presence of Leishmania braziliensis DNA in the Nasal Mucosa of Cutaneous Leishmaniasis Patients and the Search for Possible Clinical and Immunological Patterns of Disease Progression: A Cross Sectional Study
por: Barroso, Daniel Holanda, et al.
Publicado: (2021)

Increased PD-1 Level in Severe Cervical Injury Is Associated With the Rare Programmed Cell Death 1 (PDCD1) rs36084323 A Allele in a Dominant Model
por: da Silva, Mauro César, et al.
Publicado: (2021)

Antibodies Against the Plasmodium vivax Apical Membrane Antigen 1 From the Belem Strain Share Common Epitopes Among Other Worldwide Variants
por: França, Ana Caroline Barbosa, et al.
Publicado: (2021)

The Trojan Horse Model in Paracoccidioides: A Fantastic Pathway to Survive Infecting Human Cells
por: Giusiano, Gustavo
Publicado: (2021)

LAPped in Proof: LC3‐Associated Phagocytosis and the Arms Race Against Bacterial Pathogens
por: Grijmans, Bart J. M., et al.
Publicado: (2022)

Air Pollution’s Impact on Cardiac Remodeling in an Experimental Model of Chagas Cardiomyopathy
por: Fonseca, Keila Cardoso Barbosa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_46k0mughcn27v3npfbr3t926cc