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Anti-Inflammatory Effect of Geniposide on Regulating the Functions of Rheumatoid Arthritis Synovial Fibroblasts via Inhibiting Sphingosine-1-Phosphate Receptors1/3 Coupling Gαi/Gαs Conversion

The activated Gα protein subunit (Gαs) and the inhibitory Gα protein subunit (Gαi) are involved in the signal transduction of G protein coupled receptors (GPCRs). Moreover, the conversion of Gαi/Gαs can couple with sphingosine-1-phosphate receptors (S1PRs) and have a critical role in rheumatoid arth...

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Detalles Bibliográficos
Autores principales:	Wang, Rong-hui, Dai, Xue-jing, Wu, Hong, Wang, Meng-die, Deng, Ran, Wang, Yan, Bu, Yan-hong, Sun, Ming-hui, Zhang, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753157/ https://www.ncbi.nlm.nih.gov/pubmed/33363467 http://dx.doi.org/10.3389/fphar.2020.584176

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