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Progress towards elimination of lymphatic filariasis in the Americas region

In South and Central America, lymphatic filariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad an...

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Autores principales: Fontes, Gilberto, da Rocha, Eliana Maria Mauricio, Scholte, Ronaldo Guilherme Carvalho, Nicholls, Rubén Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753170/
https://www.ncbi.nlm.nih.gov/pubmed/33349876
http://dx.doi.org/10.1093/inthealth/ihaa048
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author Fontes, Gilberto
da Rocha, Eliana Maria Mauricio
Scholte, Ronaldo Guilherme Carvalho
Nicholls, Rubén Santiago
author_facet Fontes, Gilberto
da Rocha, Eliana Maria Mauricio
Scholte, Ronaldo Guilherme Carvalho
Nicholls, Rubén Santiago
author_sort Fontes, Gilberto
collection PubMed
description In South and Central America, lymphatic filariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad and Tobago were removed from the World Health Organization list in 2011. The remaining countries, Brazil, Dominican Republic, Guyana and Haiti, have achieved important progress in recent years. Brazil was the first country in the Americas to stop mass drug administration (MDA) and to establish post-MDA surveillance. Dominican Republic stopped MDA in all LF-endemic foci: La Ciénaga and Southwest passed the third Transmission Assessment Survey (TAS) and the Eastern focus passed TAS-1 in 2018. Haiti passed the TAS and interrupted transmission in >80% of endemic communes, achieving effective drug coverage. Guyana implemented effective coverage in MDAs in 2017 and 2018 and in 2019 scaled up the treatment for 100% of the geographical region, introducing ivermectin in the MDA in order to achieve LF elimination by the year 2026. The Americas region is on its way to eliminating LF transmission. However, efforts should be made to improve morbidity management to prevent disability of the already affected populations.
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spelling pubmed-77531702020-12-29 Progress towards elimination of lymphatic filariasis in the Americas region Fontes, Gilberto da Rocha, Eliana Maria Mauricio Scholte, Ronaldo Guilherme Carvalho Nicholls, Rubén Santiago Int Health Review In South and Central America, lymphatic filariasis (LF) is caused by Wuchereria bancrofti, which is transmitted by Culex quinquefasciatus, the only vector species in this region. Of the seven countries considered endemic for LF in the Americas in the last decade, Costa Rica, Suriname and Trinidad and Tobago were removed from the World Health Organization list in 2011. The remaining countries, Brazil, Dominican Republic, Guyana and Haiti, have achieved important progress in recent years. Brazil was the first country in the Americas to stop mass drug administration (MDA) and to establish post-MDA surveillance. Dominican Republic stopped MDA in all LF-endemic foci: La Ciénaga and Southwest passed the third Transmission Assessment Survey (TAS) and the Eastern focus passed TAS-1 in 2018. Haiti passed the TAS and interrupted transmission in >80% of endemic communes, achieving effective drug coverage. Guyana implemented effective coverage in MDAs in 2017 and 2018 and in 2019 scaled up the treatment for 100% of the geographical region, introducing ivermectin in the MDA in order to achieve LF elimination by the year 2026. The Americas region is on its way to eliminating LF transmission. However, efforts should be made to improve morbidity management to prevent disability of the already affected populations. Oxford University Press 2020-12-22 /pmc/articles/PMC7753170/ /pubmed/33349876 http://dx.doi.org/10.1093/inthealth/ihaa048 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review
Fontes, Gilberto
da Rocha, Eliana Maria Mauricio
Scholte, Ronaldo Guilherme Carvalho
Nicholls, Rubén Santiago
Progress towards elimination of lymphatic filariasis in the Americas region
title Progress towards elimination of lymphatic filariasis in the Americas region
title_full Progress towards elimination of lymphatic filariasis in the Americas region
title_fullStr Progress towards elimination of lymphatic filariasis in the Americas region
title_full_unstemmed Progress towards elimination of lymphatic filariasis in the Americas region
title_short Progress towards elimination of lymphatic filariasis in the Americas region
title_sort progress towards elimination of lymphatic filariasis in the americas region
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753170/
https://www.ncbi.nlm.nih.gov/pubmed/33349876
http://dx.doi.org/10.1093/inthealth/ihaa048
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