Cargando…
High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature
INTRODUCTION: Adenoid cystic carcinoma (ACC) is a rare tumor developed in minor salivary glands, the palate being the most common site. CASE PRESENTATION: Here, we report a case of a 58-year-old man with a 3-year-growing swelling in the right palate diagnosed with high grade transformation adenoid c...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753240/ https://www.ncbi.nlm.nih.gov/pubmed/33352446 http://dx.doi.org/10.1016/j.ijscr.2020.12.014 |
_version_ | 1783626031788195840 |
---|---|
author | Ahlem, Bchir Manel, Njima Nouha, Ben Abdeljalil Seiffeddine, Ben Hammouda Khalifa, Mighri Leila, Njim Abdelfateh, Zakhama |
author_facet | Ahlem, Bchir Manel, Njima Nouha, Ben Abdeljalil Seiffeddine, Ben Hammouda Khalifa, Mighri Leila, Njim Abdelfateh, Zakhama |
author_sort | Ahlem, Bchir |
collection | PubMed |
description | INTRODUCTION: Adenoid cystic carcinoma (ACC) is a rare tumor developed in minor salivary glands, the palate being the most common site. CASE PRESENTATION: Here, we report a case of a 58-year-old man with a 3-year-growing swelling in the right palate diagnosed with high grade transformation adenoid cystic carcinoma. The exam revealed a 4 cm large mass. A tumor resection with a radical neck dissection was performed. DISCUSSION: High grade transformation in adenoid cystic carcinoma is recently described by Cheuk et al. in 1999. This transformation has more aggressive behavior than conventional solid ACC and has usually been associated with recurrences, early distant metastasis, and greater mortality. CONCLUSION: The aim here is to highlight clinical, histopathological, therapeutic and prognostic aspects of high-grade transformation in ACC with literature review. |
format | Online Article Text |
id | pubmed-7753240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-77532402020-12-23 High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature Ahlem, Bchir Manel, Njima Nouha, Ben Abdeljalil Seiffeddine, Ben Hammouda Khalifa, Mighri Leila, Njim Abdelfateh, Zakhama Int J Surg Case Rep Case Report INTRODUCTION: Adenoid cystic carcinoma (ACC) is a rare tumor developed in minor salivary glands, the palate being the most common site. CASE PRESENTATION: Here, we report a case of a 58-year-old man with a 3-year-growing swelling in the right palate diagnosed with high grade transformation adenoid cystic carcinoma. The exam revealed a 4 cm large mass. A tumor resection with a radical neck dissection was performed. DISCUSSION: High grade transformation in adenoid cystic carcinoma is recently described by Cheuk et al. in 1999. This transformation has more aggressive behavior than conventional solid ACC and has usually been associated with recurrences, early distant metastasis, and greater mortality. CONCLUSION: The aim here is to highlight clinical, histopathological, therapeutic and prognostic aspects of high-grade transformation in ACC with literature review. Elsevier 2020-12-13 /pmc/articles/PMC7753240/ /pubmed/33352446 http://dx.doi.org/10.1016/j.ijscr.2020.12.014 Text en © 2020 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Ahlem, Bchir Manel, Njima Nouha, Ben Abdeljalil Seiffeddine, Ben Hammouda Khalifa, Mighri Leila, Njim Abdelfateh, Zakhama High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature |
title | High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature |
title_full | High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature |
title_fullStr | High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature |
title_full_unstemmed | High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature |
title_short | High grade transformation of adenoid cystic carcinoma in the palate: Case report with review of literature |
title_sort | high grade transformation of adenoid cystic carcinoma in the palate: case report with review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753240/ https://www.ncbi.nlm.nih.gov/pubmed/33352446 http://dx.doi.org/10.1016/j.ijscr.2020.12.014 |
work_keys_str_mv | AT ahlembchir highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature AT manelnjima highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature AT nouhabenabdeljalil highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature AT seiffeddinebenhammouda highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature AT khalifamighri highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature AT leilanjim highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature AT abdelfatehzakhama highgradetransformationofadenoidcysticcarcinomainthepalatecasereportwithreviewofliterature |