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Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry

OBJECTIVES: The aim of this study was to assess the impact of the coronavirus disease 2019 (COVID‐19) outbreak on incidence, delays, and outcomes of ST‐elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) in France. METHODS: We analyzed all pa...

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Autores principales: Rangé, Grégoire, Hakim, Radwan, Beygui, Farzin, Angoulvant, Denis, Marcollet, Pierre, Godin, Matthieu, Deballon, Ronan, Bonnet, Philippe, Fichaux, Olivier, Barbey, Christophe, Viallard, Louis, Lesault, Pierre Francois, Durand, Eric, Boiffard, Emmanuel, Dutheil, Gerard, Collet, Jean‐Philippe, Benamer, Hakim, Commeau, Philippe, Montalescot, Gilles, Koning, Rene, Motreff, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753646/
https://www.ncbi.nlm.nih.gov/pubmed/33363285
http://dx.doi.org/10.1002/emp2.12325
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author Rangé, Grégoire
Hakim, Radwan
Beygui, Farzin
Angoulvant, Denis
Marcollet, Pierre
Godin, Matthieu
Deballon, Ronan
Bonnet, Philippe
Fichaux, Olivier
Barbey, Christophe
Viallard, Louis
Lesault, Pierre Francois
Durand, Eric
Boiffard, Emmanuel
Dutheil, Gerard
Collet, Jean‐Philippe
Benamer, Hakim
Commeau, Philippe
Montalescot, Gilles
Koning, Rene
Motreff, Pascal
author_facet Rangé, Grégoire
Hakim, Radwan
Beygui, Farzin
Angoulvant, Denis
Marcollet, Pierre
Godin, Matthieu
Deballon, Ronan
Bonnet, Philippe
Fichaux, Olivier
Barbey, Christophe
Viallard, Louis
Lesault, Pierre Francois
Durand, Eric
Boiffard, Emmanuel
Dutheil, Gerard
Collet, Jean‐Philippe
Benamer, Hakim
Commeau, Philippe
Montalescot, Gilles
Koning, Rene
Motreff, Pascal
author_sort Rangé, Grégoire
collection PubMed
description OBJECTIVES: The aim of this study was to assess the impact of the coronavirus disease 2019 (COVID‐19) outbreak on incidence, delays, and outcomes of ST‐elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) in France. METHODS: We analyzed all patients undergoing PPCI <24 hours STEMI included in the prospective France PCI registry. The 2 groups were compared on mean monthly number of patients, delays in the pathway care, and in‐hospital major adverse cardiac events (MACE: death, stent thrombosis, myocardial infarction, unplanned coronary revascularization, stroke, and major bleeding). RESULTS: From January 15, 2019 to April 14, 2020, 2064 STEMI patients undergoing PPCI were included: 1942 in the prelockdown group and 122 in the lockdown group. Only 2 cases in the lockdown group were positive for COVID‐19. A significant drop (12%) in mean number of STEMI/month was observed in the lockdown group compared with prelockdown (139 vs 122, P < 0.04). A significant increase in “symptom onset to first medical contact” delay was found for patients who presented directly to the emergency department (ED) (238 minutes vs 450 minutes; P = 0.04). There were higher rates of in‐hospital MACE (7.7% vs 12.3%; P = 0.06) and mortality (4.9% vs 8.2%; P = 0.11) in the lockdown group but the differences were not significant. CONCLUSION: According to the multicenter France PCI registry, the COVID‐19 outbreak in France was associated with a significant decline in STEMI undergoing PPCI and longer transfer time for patients who presented directly to the ED. Mortality rates doubled, but the difference was not statistically significant.
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spelling pubmed-77536462020-12-22 Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry Rangé, Grégoire Hakim, Radwan Beygui, Farzin Angoulvant, Denis Marcollet, Pierre Godin, Matthieu Deballon, Ronan Bonnet, Philippe Fichaux, Olivier Barbey, Christophe Viallard, Louis Lesault, Pierre Francois Durand, Eric Boiffard, Emmanuel Dutheil, Gerard Collet, Jean‐Philippe Benamer, Hakim Commeau, Philippe Montalescot, Gilles Koning, Rene Motreff, Pascal J Am Coll Emerg Physicians Open Cardiology OBJECTIVES: The aim of this study was to assess the impact of the coronavirus disease 2019 (COVID‐19) outbreak on incidence, delays, and outcomes of ST‐elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) in France. METHODS: We analyzed all patients undergoing PPCI <24 hours STEMI included in the prospective France PCI registry. The 2 groups were compared on mean monthly number of patients, delays in the pathway care, and in‐hospital major adverse cardiac events (MACE: death, stent thrombosis, myocardial infarction, unplanned coronary revascularization, stroke, and major bleeding). RESULTS: From January 15, 2019 to April 14, 2020, 2064 STEMI patients undergoing PPCI were included: 1942 in the prelockdown group and 122 in the lockdown group. Only 2 cases in the lockdown group were positive for COVID‐19. A significant drop (12%) in mean number of STEMI/month was observed in the lockdown group compared with prelockdown (139 vs 122, P < 0.04). A significant increase in “symptom onset to first medical contact” delay was found for patients who presented directly to the emergency department (ED) (238 minutes vs 450 minutes; P = 0.04). There were higher rates of in‐hospital MACE (7.7% vs 12.3%; P = 0.06) and mortality (4.9% vs 8.2%; P = 0.11) in the lockdown group but the differences were not significant. CONCLUSION: According to the multicenter France PCI registry, the COVID‐19 outbreak in France was associated with a significant decline in STEMI undergoing PPCI and longer transfer time for patients who presented directly to the ED. Mortality rates doubled, but the difference was not statistically significant. John Wiley and Sons Inc. 2020-11-23 /pmc/articles/PMC7753646/ /pubmed/33363285 http://dx.doi.org/10.1002/emp2.12325 Text en © 2020 The Authors. JACEP Open published by Wiley Periodicals LLC on behalf of the American College of Emergency Physicians. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Cardiology
Rangé, Grégoire
Hakim, Radwan
Beygui, Farzin
Angoulvant, Denis
Marcollet, Pierre
Godin, Matthieu
Deballon, Ronan
Bonnet, Philippe
Fichaux, Olivier
Barbey, Christophe
Viallard, Louis
Lesault, Pierre Francois
Durand, Eric
Boiffard, Emmanuel
Dutheil, Gerard
Collet, Jean‐Philippe
Benamer, Hakim
Commeau, Philippe
Montalescot, Gilles
Koning, Rene
Motreff, Pascal
Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry
title Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry
title_full Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry
title_fullStr Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry
title_full_unstemmed Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry
title_short Incidence, delays, and outcomes of STEMI during COVID‐19 outbreak: Analysis from the France PCI registry
title_sort incidence, delays, and outcomes of stemi during covid‐19 outbreak: analysis from the france pci registry
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753646/
https://www.ncbi.nlm.nih.gov/pubmed/33363285
http://dx.doi.org/10.1002/emp2.12325
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