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Small intestinal taurochenodeoxycholic acid-FXR axis alters local nutrient-sensing glucoregulatory pathways in rats

OBJECTIVE: The mechanism of nutrient sensing in the upper small intestine (USI) and ileum that regulates glucose homeostasis remains elusive. Short-term high-fat (HF) feeding increases taurochenodeoxycholic acid (TCDCA; an agonist of farnesoid X receptor (FXR)) in the USI and ileum of rats, and the...

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Detalles Bibliográficos
Autores principales:	Waise, T.M. Zaved, Lim, Yu-Mi, Danaei, Zahra, Zhang, Song-Yang, Lam, Tony K.T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753965/ https://www.ncbi.nlm.nih.gov/pubmed/33264656 http://dx.doi.org/10.1016/j.molmet.2020.101132

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