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Nepetin inhibits osteoclastogenesis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signalling pathway, and autophagy

Aseptic prosthetic loosening due to wear particle–induced inflammatory osteolysis is the main cause of failure for artificial joint replacement. The inflammatory response and the production of pro‐osteoclastic factors lead to elevation of osteoclast formation and excessive activity results in extens...

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Detalles Bibliográficos
Autores principales: Chu, Binxiang, Chen, Shenao, Zheng, Xiaohe, Ye, Jiajing, Cheng, Xu, Zhang, Liwei, Guo, Di, Wang, Peng, Hong, Dun, Hong, Zhenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754000/
https://www.ncbi.nlm.nih.gov/pubmed/33135301
http://dx.doi.org/10.1111/jcmm.16055