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Nepetin inhibits osteoclastogenesis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signalling pathway, and autophagy
Aseptic prosthetic loosening due to wear particle–induced inflammatory osteolysis is the main cause of failure for artificial joint replacement. The inflammatory response and the production of pro‐osteoclastic factors lead to elevation of osteoclast formation and excessive activity results in extens...
Autores principales: | Chu, Binxiang, Chen, Shenao, Zheng, Xiaohe, Ye, Jiajing, Cheng, Xu, Zhang, Liwei, Guo, Di, Wang, Peng, Hong, Dun, Hong, Zhenghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754000/ https://www.ncbi.nlm.nih.gov/pubmed/33135301 http://dx.doi.org/10.1111/jcmm.16055 |
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