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The carboxy‐terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC‐activation

Autosomal recessive polycystic kidney disease (ARPKD) is mainly caused by variants in the PKHD1 gene, encoding fibrocystin (FC), a large transmembrane protein of incompletely understood cellular function. Here, we show that a C‐terminal fragment of human FC can suppress a signalling module of the ki...

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Detalles Bibliográficos
Autores principales:	Dafinger, Claudia, Mandel, Amrei M., Braun, Alina, Göbel, Heike, Burgmaier, Kathrin, Massella, Laura, Mastrangelo, Antonio, Dötsch, Jörg, Benzing, Thomas, Weimbs, Thomas, Schermer, Bernhard, Liebau, Max C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Short Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754027/ https://www.ncbi.nlm.nih.gov/pubmed/33112055 http://dx.doi.org/10.1111/jcmm.16014

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