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Molecular structure and evolution mechanism of two populations of double minutes in human colorectal cancer cells

Gene amplification chiefly manifests as homogeneously stained regions (HSRs) or double minutes (DMs) in cytogenetically and extrachromosomal DNA (ecDNA) in molecular genetics. Evidence suggests that gene amplification is becoming a hotspot for cancer research, which may be a new treatment strategy f...

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Detalles Bibliográficos
Autores principales: Jia, Xueyuan, Guan, Rongwei, Cui, Xiaobo, Zhu, Jing, Liu, Peng, Zhang, Ling, Wang, Dong, Zhang, Yang, Dong, Kexian, Wu, Jie, Ji, Wei, Ji, Guohua, Bai, Jing, Yu, Jingcui, Yu, Yang, Sun, Wenjing, Zhang, Feng, Fu, Songbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754069/
https://www.ncbi.nlm.nih.gov/pubmed/33124133
http://dx.doi.org/10.1111/jcmm.16035