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Analysis of Complex DNA Rearrangements during Early Stages of HAC Formation

[Image: see text] Human artificial chromosomes (HACs) are important tools for epigenetic engineering, for measuring chromosome instability (CIN), and for possible gene therapy. However, their use in the latter is potentially limited because the input HAC-seeding DNA can undergo an unpredictable seri...

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Detalles Bibliográficos
Autores principales:	Pesenti, Elisa, Liskovykh, Mikhail, Okazaki, Koei, Mallozzi, Alessio, Reid, Caitlin, Abad, Maria Alba, Jeyaprakash, A. Arockia, Kouprina, Natalay, Larionov, Vladimir, Masumoto, Hiroshi, Earnshaw, William C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754191/ https://www.ncbi.nlm.nih.gov/pubmed/33289546 http://dx.doi.org/10.1021/acssynbio.0c00326

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