SynGAP splice variants display heterogeneous spatio‐temporal expression and subcellular distribution in the developing mammalian brain

The SynGAP protein is a major regulator of synapse biology and neural circuit function. Genetic variants linked to epilepsy and intellectual disability disrupt synaptic function and neural excitability. SynGAP has been involved in multiple signaling pathways and can regulate small GTPases with very...

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Detalles Bibliográficos
Autores principales: Gou, Gemma, Roca‐Fernandez, Adriana, Kilinc, Murat, Serrano, Elena, Reig‐Viader, Rita, Araki, Yoichi, Huganir, Richard L., de Quintana‐Schmidt, Cristian, Rumbaugh, Gavin, Bayés, Àlex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754318/
https://www.ncbi.nlm.nih.gov/pubmed/32068252
http://dx.doi.org/10.1111/jnc.14988

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