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Population Pharmacokinetics and Exposure‐Response Relationship of Luspatercept, an Erythroid Maturation Agent, in Anemic Patients With β‐Thalassemia

β‐Thalassemia is an inherited blood disorder resulting from defects in hemoglobin production, leading to premature death of red blood cells (RBCs) or their precursors. Patients with transfusion‐dependent β‐thalassemia often need lifelong regular RBC transfusions to maintain adequate hemoglobin level...

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Detalles Bibliográficos
Autores principales: Chen, Nianhang, Kassir, Nastya, Laadem, Abderrahmane, Giuseppi, Ana Carolina, Shetty, Jeevan, Maxwell, Stephen E., Sriraman, Priya, Ritland, Steve, Linde, Peter G., Budda, Balasubrahmanyam, Reynolds, Joseph G., Zhou, Simon, Palmisano, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754485/
https://www.ncbi.nlm.nih.gov/pubmed/32696522
http://dx.doi.org/10.1002/jcph.1696

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