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7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms

BACKGROUND AND PURPOSE: Aneurysm size and neck measurements are important for treatment decisions. The introduction of 7T magnetic resonance angiography (MRA) led to new possibilities assessing aneurysm morphology and flow due to the higher signal‐to‐noise ratio. However, it is unknown if the size m...

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Autores principales: Leemans, Eva, Cornelissen, Bart, Sing, M. L. C., Sprengers, Marieke, van den Berg, Rene, Roos, Yvo, Vandertop, W. Pieter, Slump, Cornelius, Marquering, Henk, Majoie, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754498/
https://www.ncbi.nlm.nih.gov/pubmed/32857906
http://dx.doi.org/10.1111/jon.12772
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author Leemans, Eva
Cornelissen, Bart
Sing, M. L. C.
Sprengers, Marieke
van den Berg, Rene
Roos, Yvo
Vandertop, W. Pieter
Slump, Cornelius
Marquering, Henk
Majoie, Charles
author_facet Leemans, Eva
Cornelissen, Bart
Sing, M. L. C.
Sprengers, Marieke
van den Berg, Rene
Roos, Yvo
Vandertop, W. Pieter
Slump, Cornelius
Marquering, Henk
Majoie, Charles
author_sort Leemans, Eva
collection PubMed
description BACKGROUND AND PURPOSE: Aneurysm size and neck measurements are important for treatment decisions. The introduction of 7T magnetic resonance angiography (MRA) led to new possibilities assessing aneurysm morphology and flow due to the higher signal‐to‐noise ratio. However, it is unknown if the size measurements on 7T MRA are similar to those on the standard 3T MRA. This study aimed to compare aneurysm size measurements between 7T and 3T MRA. METHODS: We included 18 patients with 22 aneurysms who underwent both 3T and 7T MRA. Three acquisition protocols were compared: 3T time of flight (TOF), 7T TOF, and 7T contrast‐enhanced MRA. Each aneurysm on each protocol was measured by at least two experienced neuroradiologists. Subsequently, the differences were evaluated using scatterplots and the intraclass correlation coefficients (ICC) of agreement. RESULTS: There was a good agreement among the neuroradiologists for the height and width measurements (mean ICC: .78‐.93); the neck measurements showed a moderate agreement with a mean ICC of .57‐.72. Between the MR acquisition protocols, there was a high agreement for all measurements with a mean ICC of .81‐.96. Measurement differences between acquisition protocols (0‐2.9 mm) were in the range of the differences between the neuroradiologists (0‐3.6 mm). CONCLUSION: Our study showed that 7T MRA, both nonenhanced and contrast‐enhanced, has a high agreement in aneurysm size measurements compared to 3T. This suggests that 7T is useful for reliable aneurysm size assessment.
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spelling pubmed-77544982020-12-28 7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms Leemans, Eva Cornelissen, Bart Sing, M. L. C. Sprengers, Marieke van den Berg, Rene Roos, Yvo Vandertop, W. Pieter Slump, Cornelius Marquering, Henk Majoie, Charles J Neuroimaging Original Research BACKGROUND AND PURPOSE: Aneurysm size and neck measurements are important for treatment decisions. The introduction of 7T magnetic resonance angiography (MRA) led to new possibilities assessing aneurysm morphology and flow due to the higher signal‐to‐noise ratio. However, it is unknown if the size measurements on 7T MRA are similar to those on the standard 3T MRA. This study aimed to compare aneurysm size measurements between 7T and 3T MRA. METHODS: We included 18 patients with 22 aneurysms who underwent both 3T and 7T MRA. Three acquisition protocols were compared: 3T time of flight (TOF), 7T TOF, and 7T contrast‐enhanced MRA. Each aneurysm on each protocol was measured by at least two experienced neuroradiologists. Subsequently, the differences were evaluated using scatterplots and the intraclass correlation coefficients (ICC) of agreement. RESULTS: There was a good agreement among the neuroradiologists for the height and width measurements (mean ICC: .78‐.93); the neck measurements showed a moderate agreement with a mean ICC of .57‐.72. Between the MR acquisition protocols, there was a high agreement for all measurements with a mean ICC of .81‐.96. Measurement differences between acquisition protocols (0‐2.9 mm) were in the range of the differences between the neuroradiologists (0‐3.6 mm). CONCLUSION: Our study showed that 7T MRA, both nonenhanced and contrast‐enhanced, has a high agreement in aneurysm size measurements compared to 3T. This suggests that 7T is useful for reliable aneurysm size assessment. John Wiley and Sons Inc. 2020-08-28 2020 /pmc/articles/PMC7754498/ /pubmed/32857906 http://dx.doi.org/10.1111/jon.12772 Text en © 2020 The Authors. Journal of Neuroimaging published by Wiley Periodicals LLC on behalf of American Society of Neuroimaging This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Leemans, Eva
Cornelissen, Bart
Sing, M. L. C.
Sprengers, Marieke
van den Berg, Rene
Roos, Yvo
Vandertop, W. Pieter
Slump, Cornelius
Marquering, Henk
Majoie, Charles
7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
title 7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
title_full 7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
title_fullStr 7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
title_full_unstemmed 7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
title_short 7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
title_sort 7t versus 3t mr angiography to assess unruptured intracranial aneurysms
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754498/
https://www.ncbi.nlm.nih.gov/pubmed/32857906
http://dx.doi.org/10.1111/jon.12772
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