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Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway

BACKGROUND: Liver fibrosis progressing to liver cirrhosis and hepatic carcinoma is very common and causes more than one million deaths annually. Fibrosis develops from recurrent liver injury but the molecular mechanisms are not fully understood. Recently, the TLR4-MyD88 signaling pathway has been re...

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Detalles Bibliográficos
Autores principales:	Wang, Zhi, Cheng, Zhen-Xing, Abrams, Simon T, Lin, Zi-Qi, Yates, ED, Yu, Qian, Yu, Wei-Ping, Chen, Ping-Sheng, Toh, Cheng-Hock, Wang, Guo-Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2020
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754552/ https://www.ncbi.nlm.nih.gov/pubmed/33384551 http://dx.doi.org/10.3748/wjg.v26.i47.7513

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