Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery

BACKGROUND: A major task of the endosomal sorting complex required for transport (ESCRT) machinery is the pinching off of cargo-loaded intraluminal vesicles (ILVs) into the lumen of maturing endosomes (MEs), which is essential for the complete degradation of transmembrane proteins in the lysosome. T...

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Detalles Bibliográficos
Autores principales: Baeumers, Miriam, Ruhnau, Kristina, Breuer, Thomas, Pannen, Hendrik, Goerlich, Bastian, Kniebel, Anna, Haensch, Sebastian, Weidtkamp-Peters, Stefanie, Schmitt, Lutz, Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754597/
https://www.ncbi.nlm.nih.gov/pubmed/33349255
http://dx.doi.org/10.1186/s12915-020-00933-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754597/
https://www.ncbi.nlm.nih.gov/pubmed/33349255
http://dx.doi.org/10.1186/s12915-020-00933-x

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