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Understanding adverse events of immunotherapy: A mechanistic perspective
The treatment of many cancers has been revolutionized by immune checkpoint blockade (ICB) as a standard-of-care therapeutic. Despite many successes, a large proportion of patients treated with ICB agents experience immune-related adverse events (irAEs) in the form of clinical autoimmunity, ranging f...
Autores principales: | Burke, Kelly P., Grebinoski, Stephanie, Sharpe, Arlene H., Vignali, Dario A.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754677/ https://www.ncbi.nlm.nih.gov/pubmed/33601411 http://dx.doi.org/10.1084/jem.20192179 |
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