Cargando…

Gatekeepers of the fetus: Characterization of placental macrophages

In this issue of JEM, Thomas et al. (https://doi.org/10.1084/jem.20200891) provide elegant technological and conceptual advances that further our understanding of the immune cells enriched at the maternal–fetal interface. Using new isolation strategies to better separate maternal- and fetal-derived...

Descripción completa

Detalles Bibliográficos
Autores principales: Megli, Christina, Coyne, Carolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754679/
https://www.ncbi.nlm.nih.gov/pubmed/33601417
http://dx.doi.org/10.1084/jem.20202071
_version_ 1783626240121372672
author Megli, Christina
Coyne, Carolyn B.
author_facet Megli, Christina
Coyne, Carolyn B.
author_sort Megli, Christina
collection PubMed
description In this issue of JEM, Thomas et al. (https://doi.org/10.1084/jem.20200891) provide elegant technological and conceptual advances that further our understanding of the immune cells enriched at the maternal–fetal interface. Using new isolation strategies to better separate maternal- and fetal-derived cells, the authors identify previously undefined maternal-derived immune cells associated with the fetal-derived placenta and provide an in-depth analysis of the markers and characteristics of placental Hofbauer cells.
format Online
Article
Text
id pubmed-7754679
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-77546792021-07-04 Gatekeepers of the fetus: Characterization of placental macrophages Megli, Christina Coyne, Carolyn B. J Exp Med Insights In this issue of JEM, Thomas et al. (https://doi.org/10.1084/jem.20200891) provide elegant technological and conceptual advances that further our understanding of the immune cells enriched at the maternal–fetal interface. Using new isolation strategies to better separate maternal- and fetal-derived cells, the authors identify previously undefined maternal-derived immune cells associated with the fetal-derived placenta and provide an in-depth analysis of the markers and characteristics of placental Hofbauer cells. Rockefeller University Press 2020-12-21 /pmc/articles/PMC7754679/ /pubmed/33601417 http://dx.doi.org/10.1084/jem.20202071 Text en © 2020 Megli and Coyne http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Megli, Christina
Coyne, Carolyn B.
Gatekeepers of the fetus: Characterization of placental macrophages
title Gatekeepers of the fetus: Characterization of placental macrophages
title_full Gatekeepers of the fetus: Characterization of placental macrophages
title_fullStr Gatekeepers of the fetus: Characterization of placental macrophages
title_full_unstemmed Gatekeepers of the fetus: Characterization of placental macrophages
title_short Gatekeepers of the fetus: Characterization of placental macrophages
title_sort gatekeepers of the fetus: characterization of placental macrophages
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754679/
https://www.ncbi.nlm.nih.gov/pubmed/33601417
http://dx.doi.org/10.1084/jem.20202071
work_keys_str_mv AT meglichristina gatekeepersofthefetuscharacterizationofplacentalmacrophages
AT coynecarolynb gatekeepersofthefetuscharacterizationofplacentalmacrophages