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Sis1 delivers the State of the Union
The heat shock response (HSR) is a gene expression program that protects cells from heat and proteotoxic stressors. In this issue, Feder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202005165) show that subcellular relocalization of the cochaperone Sis1 drives the HSR by de-suppressing th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754686/ https://www.ncbi.nlm.nih.gov/pubmed/33332552 http://dx.doi.org/10.1083/jcb.202011093 |
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author | Khan, Danish Brandman, Onn |
author_facet | Khan, Danish Brandman, Onn |
author_sort | Khan, Danish |
collection | PubMed |
description | The heat shock response (HSR) is a gene expression program that protects cells from heat and proteotoxic stressors. In this issue, Feder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202005165) show that subcellular relocalization of the cochaperone Sis1 drives the HSR by de-suppressing the transcription factor Hsf1. |
format | Online Article Text |
id | pubmed-7754686 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-77546862021-07-04 Sis1 delivers the State of the Union Khan, Danish Brandman, Onn J Cell Biol Spotlight The heat shock response (HSR) is a gene expression program that protects cells from heat and proteotoxic stressors. In this issue, Feder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202005165) show that subcellular relocalization of the cochaperone Sis1 drives the HSR by de-suppressing the transcription factor Hsf1. Rockefeller University Press 2020-12-17 /pmc/articles/PMC7754686/ /pubmed/33332552 http://dx.doi.org/10.1083/jcb.202011093 Text en © 2020 Khan and Brandman http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Spotlight Khan, Danish Brandman, Onn Sis1 delivers the State of the Union |
title | Sis1 delivers the State of the Union |
title_full | Sis1 delivers the State of the Union |
title_fullStr | Sis1 delivers the State of the Union |
title_full_unstemmed | Sis1 delivers the State of the Union |
title_short | Sis1 delivers the State of the Union |
title_sort | sis1 delivers the state of the union |
topic | Spotlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754686/ https://www.ncbi.nlm.nih.gov/pubmed/33332552 http://dx.doi.org/10.1083/jcb.202011093 |
work_keys_str_mv | AT khandanish sis1deliversthestateoftheunion AT brandmanonn sis1deliversthestateoftheunion |