Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy

AIMS: Duchenne muscular dystrophy (DMD) is an X‐linked inherited disease due to dystrophin deficiency causing skeletal and cardiac muscle dysfunction. Affected patients lose ambulation by age 12 and usually die in the second to third decades of life from cardiac and respiratory failure. Symptomatic...

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Detalles Bibliográficos
Autores principales: Lowe, Jeovanna, Kolkhof, Peter, Haupt, Michael J., Peczkowski, Kyra K., Rastogi, Neha, Hauck, J. Spencer, Kadakia, Feni K., Zins, Jonathan G., Ciccone, Pierce C., Smart, Suzanne, Sandner, Peter, Raman, Subha V., Janssen, Paul M.L., Rafael‐Fortney, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754779/
https://www.ncbi.nlm.nih.gov/pubmed/32945624
http://dx.doi.org/10.1002/ehf2.12996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754779/
https://www.ncbi.nlm.nih.gov/pubmed/32945624
http://dx.doi.org/10.1002/ehf2.12996

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