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Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy

AIMS: Although some peripartum‐associated cardiomyopathy patients present with features that are clinically and echocardiographically similar to those of takotsubo cardiomyopathy (TCM), little is known about the diagnosis and clinical course of peripartum TCM. METHODS AND RESULTS: In a tertiary hosp...

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Autores principales: Kim, Dong‐Yeon, Kim, So Ree, Park, Sung‐Ji, Seo, Jeong‐Hun, Kim, Eun Kyoung, Yang, Jeong Hoon, Chang, Sung‐A, Choi, Jin‐Oh, Lee, Sang‐Chol, Park, Seung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754891/
https://www.ncbi.nlm.nih.gov/pubmed/32896987
http://dx.doi.org/10.1002/ehf2.12889
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author Kim, Dong‐Yeon
Kim, So Ree
Park, Sung‐Ji
Seo, Jeong‐Hun
Kim, Eun Kyoung
Yang, Jeong Hoon
Chang, Sung‐A
Choi, Jin‐Oh
Lee, Sang‐Chol
Park, Seung Woo
author_facet Kim, Dong‐Yeon
Kim, So Ree
Park, Sung‐Ji
Seo, Jeong‐Hun
Kim, Eun Kyoung
Yang, Jeong Hoon
Chang, Sung‐A
Choi, Jin‐Oh
Lee, Sang‐Chol
Park, Seung Woo
author_sort Kim, Dong‐Yeon
collection PubMed
description AIMS: Although some peripartum‐associated cardiomyopathy patients present with features that are clinically and echocardiographically similar to those of takotsubo cardiomyopathy (TCM), little is known about the diagnosis and clinical course of peripartum TCM. METHODS AND RESULTS: In a tertiary hospital in Seoul, Korea, we searched the hospital database to find cardiomyopathy cases that were associated with pregnancy from January 1995 to May 2019. Applying the published diagnostic criteria, we sought peripartum cardiomyopathy (PPCM) and peripartum TCM patients for comparison. Of 31 pregnancy‐associated cardiomyopathy patients, 10 cases of peripartum TCM and 21 cases of PPCM were found. Maternal near‐miss death was significantly more common in the peripartum TCM group than in the PPCM group (100.0% vs. 57.1%, P = 0.030). Complete recovery was observed with all peripartum TCM cases, while 23.8% of the PPCM cases had residual left ventricular dysfunction. One death and one heart transplantation occurred in the PPCM group, while neither occurred in the peripartum TCM group. There was no difference between the two groups in terms of the rate of major adverse clinical events at 3 years of follow‐up [PPCM group: 26.3% (5/19) vs. TCM group: 33.3% (3/9), P = 0.750]. CONCLUSIONS: One‐third of pregnancy‐associated cardiomyopathy patients had peripartum TCM. With contemporary supportive care, both PPCM and peripartum TCM patients had a low mortality rate and excellent long‐term outcomes.
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spelling pubmed-77548912020-12-23 Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy Kim, Dong‐Yeon Kim, So Ree Park, Sung‐Ji Seo, Jeong‐Hun Kim, Eun Kyoung Yang, Jeong Hoon Chang, Sung‐A Choi, Jin‐Oh Lee, Sang‐Chol Park, Seung Woo ESC Heart Fail Original Research Articles AIMS: Although some peripartum‐associated cardiomyopathy patients present with features that are clinically and echocardiographically similar to those of takotsubo cardiomyopathy (TCM), little is known about the diagnosis and clinical course of peripartum TCM. METHODS AND RESULTS: In a tertiary hospital in Seoul, Korea, we searched the hospital database to find cardiomyopathy cases that were associated with pregnancy from January 1995 to May 2019. Applying the published diagnostic criteria, we sought peripartum cardiomyopathy (PPCM) and peripartum TCM patients for comparison. Of 31 pregnancy‐associated cardiomyopathy patients, 10 cases of peripartum TCM and 21 cases of PPCM were found. Maternal near‐miss death was significantly more common in the peripartum TCM group than in the PPCM group (100.0% vs. 57.1%, P = 0.030). Complete recovery was observed with all peripartum TCM cases, while 23.8% of the PPCM cases had residual left ventricular dysfunction. One death and one heart transplantation occurred in the PPCM group, while neither occurred in the peripartum TCM group. There was no difference between the two groups in terms of the rate of major adverse clinical events at 3 years of follow‐up [PPCM group: 26.3% (5/19) vs. TCM group: 33.3% (3/9), P = 0.750]. CONCLUSIONS: One‐third of pregnancy‐associated cardiomyopathy patients had peripartum TCM. With contemporary supportive care, both PPCM and peripartum TCM patients had a low mortality rate and excellent long‐term outcomes. John Wiley and Sons Inc. 2020-09-08 /pmc/articles/PMC7754891/ /pubmed/32896987 http://dx.doi.org/10.1002/ehf2.12889 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research Articles
Kim, Dong‐Yeon
Kim, So Ree
Park, Sung‐Ji
Seo, Jeong‐Hun
Kim, Eun Kyoung
Yang, Jeong Hoon
Chang, Sung‐A
Choi, Jin‐Oh
Lee, Sang‐Chol
Park, Seung Woo
Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
title Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
title_full Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
title_fullStr Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
title_full_unstemmed Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
title_short Clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
title_sort clinical characteristics and long‐term outcomes of peripartum takotsubo cardiomyopathy and peripartum cardiomyopathy
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754891/
https://www.ncbi.nlm.nih.gov/pubmed/32896987
http://dx.doi.org/10.1002/ehf2.12889
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