Rapid, point-of-care molecular diagnostics with Cas13

Rapid nucleic acid testing is a critical component of a robust infrastructure for increased disease surveillance. Here, we report a microfluidic platform for point-of-care, CRISPR-based molecular diagnostics. We first developed a nucleic acid test which pairs distinct mechanisms of DNA and RNA ampli...

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Detalles Bibliográficos
Autores principales: Agrawal, Shreeya, Fanton, Alison, Chandrasekaran, Sita S., Charrez, Bérénice, Escajeda, Arturo M., Son, Sungmin, Mcintosh, Roger, Bhuiya, Abdul, de León Derby, María Díaz, Switz, Neil A., Armstrong, Maxim, Harris, Andrew R., Prywes, Noam, Lukarska, Maria, Biering, Scott B., Smock, Dylan C. J., Mok, Amanda, Knott, Gavin J., Dang, Qi, Van Dis, Erik, Dugan, Eli, Kim, Shin, Liu, Tina Y., Harris, Eva, Stanley, Sarah A., Lareau, Liana F., Tan, Ming X., Fletcher, Daniel A., Doudna, Jennifer A., Savage, David F., Hsu, Patrick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755151/
https://www.ncbi.nlm.nih.gov/pubmed/33354689
http://dx.doi.org/10.1101/2020.12.14.20247874

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