Cargando…

Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis

Hypoxia-induced angiogenesis maintains tissue oxygen supply and protects against ischemia but also enhances tumor progression and malignancy. This is mediated through activation of transcription factors like hypoxia-inducible factor 1 (HIF-1) and c-Myc, yet the impact of hypoxia on negative regulato...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Yi, Liu, Ze, Zhang, Qian, Vallee, Ingrid, Mo, Zhongying, Kishi, Shuji, Yang, Xiang-Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755189/ https://www.ncbi.nlm.nih.gov/pubmed/33351793 http://dx.doi.org/10.1371/journal.pbio.3000991

Ejemplares similares

Insights into substrate promiscuity of human seryl-tRNA synthetase
por: Holman, Kaitlyn M., et al.
Publicado: (2017)

Clone and functional analysis of Seryl-tRNA synthetase and Tyrosyl-tRNA synthetase from silkworm, Bombyx mori
por: Hu, Jingsheng, et al.
Publicado: (2017)

Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase
por: de Potter, Bastiaan, et al.
Publicado: (2023)

Glucose-sensitive acetylation of Seryl tRNA synthetase regulates lipid synthesis in breast cancer
por: Zhao, Jin, et al.
Publicado: (2021)

Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence
por: Li, Yingxi, et al.
Publicado: (2019)

Functional Epigenetic Analysis of Prostate Carcinoma: A Role for Seryl-tRNA Synthetase?
por: Ikromov, Odiljon, et al.
Publicado: (2014)

Novel variants of seryl-tRNA synthetase resulting in HUPRA syndrome featured in pulmonary hypertension
por: Yang, Fan, et al.
Publicado: (2023)

Multi-Omics Database Analysis of Aminoacyl-tRNA Synthetases in Cancer
por: Wang, Justin, et al.
Publicado: (2020)

Selective degradation of tRNA(Ser)(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease
por: Yu, Tingting, et al.
Publicado: (2022)

Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery
por: Liu, Ze, et al.
Publicado: (2023)

Loss of seryl-tRNA synthetase (SARS1) causes complex spastic paraplegia and cellular senescence
por: Verdura, Edgard, et al.
Publicado: (2022)

tRNA synthetase counteracts c-Myc to develop functional vasculature
por: Shi, Yi, et al.
Publicado: (2014)

A new mutation in the gene encoding mitochondrial seryl-tRNA synthetase as a cause of HUPRA syndrome
por: Rivera, Henry, et al.
Publicado: (2013)

Seryl-tRNA synthetase is involved in methionine stimulation of β-casein synthesis in bovine mammary epithelial cells
por: Dai, Wenting, et al.
Publicado: (2019)

Unique domain appended to vertebrate tRNA synthetase is essential for vascular development
por: Xu, Xiaoling, et al.
Publicado: (2012)

Competitive binding between Seryl-tRNA synthetase/YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis
por: Fu, Chuan-Yang, et al.
Publicado: (2017)

Regulation of Angiogenesis by Aminoacyl-tRNA Synthetases
por: Mirando, Adam C., et al.
Publicado: (2014)

Neddylation requires glycyl-tRNA synthetase to protect activated E2
por: Mo, Zhongying, et al.
Publicado: (2016)

Seryl-tRNA Synthetase Shows a Noncanonical Activity of Upregulating Laccase Transcription in Trametes hirsuta AH28-2 Exposed to Copper Ion
por: Gan, Zhiwei, et al.
Publicado: (2023)

Developmental Angiogenesis Requires the Mitochondrial Phenylalanyl-tRNA Synthetase
por: Li, Bowen, et al.
Publicado: (2021)

Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations
por: Sun, Jiying, et al.
Publicado: (2018)

Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma: ATM, ATR and FA in lung carcinoma
por: Beumer, Jan H., et al.
Publicado: (2015)

Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond
por: Galindo-Feria, Angeles S., et al.
Publicado: (2022)

A Leucyl-tRNA Synthetase Urzyme: Authenticity of tRNA Synthetase Catalytic Activities and Promiscuous Phosphorylation of Leucyl-5′AMP
por: Hobson, Jessica J., et al.
Publicado: (2022)

The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation
por: Fan, Guangjian, et al.
Publicado: (2021)

Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis
por: Williams, Tamara F., et al.
Publicado: (2013)

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress
por: Liu, Shengqin, et al.
Publicado: (2012)

Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1
por: Penedos, Ana, et al.
Publicado: (2015)

Bacterial Aspartyl-tRNA Synthetase Has Glutamyl-tRNA Synthetase Activity
por: Rathnayake, Udumbara M., et al.
Publicado: (2019)

Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
por: Khan, Krishnendu, et al.
Publicado: (2022)

Essentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatis
por: Ravishankar, Sudha, et al.
Publicado: (2016)

Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor
por: Mirando, Adam C., et al.
Publicado: (2015)

Aminoacyl-tRNA synthetases
por: Rubio Gomez, Miguel Angel, et al.
Publicado: (2020)

Expanding a tyrosyl-tRNA synthetase assay to other aminoacyl-tRNA synthetases
por: Richardson, Charles J., et al.
Publicado: (2015)

Correction: Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1
por: Penedos, Ana, et al.
Publicado: (2016)

"ATR activation in response to ionizing radiation: still ATM territory"
por: Cuadrado, Myriam, et al.
Publicado: (2006)

Decoding the impact of disease-causing mutations in an essential aminoacyl-tRNA synthetase
por: Sissler, Marie
Publicado: (2021)

Brugia malayi Asparaginyl - tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis
por: D, Jeeva Jothi, et al.
Publicado: (2016)

eIF3a‐PPP2R5A‐mediated ATM/ATR dephosphorylation is essential for irinotecan‐induced DNA damage response
por: Mei, Chao, et al.
Publicado: (2022)

Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
por: Kim, Dong Kyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f48ec01gr1d8n1lso8tiqc201s