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Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation

INTRODUCTION: vaso-occlusive crises (VOCs) are the primary reason for admission and hospitalization in children with sickle cell disease and most often they require home care before arriving to consultation. The purpose of this study was to describe home-based therapy for children with sickle cell d...

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Autores principales: Nicole, Alima Yanda Anastasie, Charlotte, Eposse Ekoube, Shanti, Ngatsing Christelle, Edgar, Mandeng Ma Linwa, Foute, Françoise Ngnedjou Nwabufor, Patrick, Ngou, Ritha, Mbono, Yolande, Djike Puepi, Patricia, Epee, Estelle, Wete, Olivier, Koki Ndombo Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755375/
https://www.ncbi.nlm.nih.gov/pubmed/33425160
http://dx.doi.org/10.11604/pamj.2020.37.127.25062
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author Nicole, Alima Yanda Anastasie
Charlotte, Eposse Ekoube
Shanti, Ngatsing Christelle
Edgar, Mandeng Ma Linwa
Foute, Françoise Ngnedjou Nwabufor
Patrick, Ngou
Ritha, Mbono
Yolande, Djike Puepi
Patricia, Epee
Estelle, Wete
Olivier, Koki Ndombo Paul
author_facet Nicole, Alima Yanda Anastasie
Charlotte, Eposse Ekoube
Shanti, Ngatsing Christelle
Edgar, Mandeng Ma Linwa
Foute, Françoise Ngnedjou Nwabufor
Patrick, Ngou
Ritha, Mbono
Yolande, Djike Puepi
Patricia, Epee
Estelle, Wete
Olivier, Koki Ndombo Paul
author_sort Nicole, Alima Yanda Anastasie
collection PubMed
description INTRODUCTION: vaso-occlusive crises (VOCs) are the primary reason for admission and hospitalization in children with sickle cell disease and most often they require home care before arriving to consultation. The purpose of this study was to describe home-based therapy for children with sickle cell disease admitted with VOCs. METHODS: we conducted a descriptive and analytical cross-sectional study, in the pediatric emergencies at the Mother and Child Centre of the Chantal Biya Foundation (CBF) over a 4-month period from February to May 2018. Consecutive sampling was used. All patients with sickle cell disease presenting with VOCs were included in the study. RESULTS: one hundred and fifty-two patients were enrolled. The most represented age group was 5- 10 years. Eighty-two patients (54%) presented more than 24 hours after the onset of the crises and 70 (46%) in the first 24 hours; 80% (n=122) of our sample had received analgesic treatment at home. Escalation of therapy was found in 31.2% of cases. The use of prescription medications (75.4%, n=92) was dominant as the 1(st) recourse. The dosage for analgesics was not correct in 67% of cases (overdose in 70% of cases). The correct dosage of home-based analgesics was administered in only 33% of patients. CONCLUSION: this study shows that home-based management of VOCs is inadequate. Measures must be taken to ensure that all patients with sickle cell disease can effectively manage minor to moderate VOCs at home.
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spelling pubmed-77553752021-01-07 Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation Nicole, Alima Yanda Anastasie Charlotte, Eposse Ekoube Shanti, Ngatsing Christelle Edgar, Mandeng Ma Linwa Foute, Françoise Ngnedjou Nwabufor Patrick, Ngou Ritha, Mbono Yolande, Djike Puepi Patricia, Epee Estelle, Wete Olivier, Koki Ndombo Paul Pan Afr Med J Research INTRODUCTION: vaso-occlusive crises (VOCs) are the primary reason for admission and hospitalization in children with sickle cell disease and most often they require home care before arriving to consultation. The purpose of this study was to describe home-based therapy for children with sickle cell disease admitted with VOCs. METHODS: we conducted a descriptive and analytical cross-sectional study, in the pediatric emergencies at the Mother and Child Centre of the Chantal Biya Foundation (CBF) over a 4-month period from February to May 2018. Consecutive sampling was used. All patients with sickle cell disease presenting with VOCs were included in the study. RESULTS: one hundred and fifty-two patients were enrolled. The most represented age group was 5- 10 years. Eighty-two patients (54%) presented more than 24 hours after the onset of the crises and 70 (46%) in the first 24 hours; 80% (n=122) of our sample had received analgesic treatment at home. Escalation of therapy was found in 31.2% of cases. The use of prescription medications (75.4%, n=92) was dominant as the 1(st) recourse. The dosage for analgesics was not correct in 67% of cases (overdose in 70% of cases). The correct dosage of home-based analgesics was administered in only 33% of patients. CONCLUSION: this study shows that home-based management of VOCs is inadequate. Measures must be taken to ensure that all patients with sickle cell disease can effectively manage minor to moderate VOCs at home. The African Field Epidemiology Network 2020-10-05 /pmc/articles/PMC7755375/ /pubmed/33425160 http://dx.doi.org/10.11604/pamj.2020.37.127.25062 Text en Copyright: Alima Yanda Anastasie Nicole et al. https://creativecommons.org/licenses/by/4.0 The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Nicole, Alima Yanda Anastasie
Charlotte, Eposse Ekoube
Shanti, Ngatsing Christelle
Edgar, Mandeng Ma Linwa
Foute, Françoise Ngnedjou Nwabufor
Patrick, Ngou
Ritha, Mbono
Yolande, Djike Puepi
Patricia, Epee
Estelle, Wete
Olivier, Koki Ndombo Paul
Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
title Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
title_full Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
title_fullStr Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
title_full_unstemmed Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
title_short Traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
title_sort traitement antalgique des crises vaso-occlusives à domicile avant l’arrivée en consultation
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755375/
https://www.ncbi.nlm.nih.gov/pubmed/33425160
http://dx.doi.org/10.11604/pamj.2020.37.127.25062
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