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Biologically Active TNIIIA2 Region in Tenascin-C Molecule: A Major Contributor to Elicit Aggressive Malignant Phenotypes From Tumors/Tumor Stroma

Tenascin (TN)-C is highly expressed specifically in the lesions of inflammation-related diseases, including tumors. The expression level of TN-C in tumors and the tumor stroma is positively correlated with poor prognosis. However, no drugs targeting TN-C are currently clinically available, partly be...

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Detalles Bibliográficos
Autores principales: Iyoda, Takuya, Fujita, Motomichi, Fukai, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755593/
https://www.ncbi.nlm.nih.gov/pubmed/33362799
http://dx.doi.org/10.3389/fimmu.2020.610096

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