Transcriptional analysis of metastatic uveal melanoma survival nominates NRP1 as a therapeutic target

Uveal melanoma is a rare form of melanoma with particularly poor outcomes in the metastatic setting. In contrast with cutaneous melanoma, uveal melanoma lacks BRAF mutations and demonstrates very low response rates to immune-checkpoint blockade. Our objectives were to study the transcriptomics of me...

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Detalles Bibliográficos
Autores principales: Bao, Riyue, Surriga, Oliver, Olson, Daniel J., Allred, Jacob B., Strand, Carrie A., Zha, Yuanyuan, Carll, Timothy, Labadie, Brian W., Bastos, Bruno R., Butler, Marcus, Hogg, David, Musi, Elgilda, Ambrosini, Grazia, Munster, Pamela, Schwartz, Gary K., Luke, Jason J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Articles: Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755667/
https://www.ncbi.nlm.nih.gov/pubmed/33170593
http://dx.doi.org/10.1097/CMR.0000000000000701

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