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Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans
Expression of abnormally long polyglutamine (polyQ) tracks is the source of a range of dominant neurodegenerative diseases, such as Huntington disease. Currently, there is no treatment for this devastating disease, although some chemicals, e.g., metformin, have been proposed as therapeutic solutions...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755709/ https://www.ncbi.nlm.nih.gov/pubmed/32739430 http://dx.doi.org/10.1016/j.phrs.2020.105105 |