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Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
2,3-Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, we describe a method that enables direct access to these core structures from non-conjugated alkenyl amides and ortho-iodoanilines/phenols. Under palladium(II) catalysis this [3 + 2] heteroannula...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755910/ https://www.ncbi.nlm.nih.gov/pubmed/33353940 http://dx.doi.org/10.1038/s41467-020-20182-4 |