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Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction

The actin-related protein (Arp)2/3 complex nucleates branched actin filament networks pivotal for cell migration, endocytosis and pathogen infection. Its activation is tightly regulated and involves complex structural rearrangements and actin filament binding, which are yet to be understood. Here, w...

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Detalles Bibliográficos
Autores principales: Fäßler, Florian, Dimchev, Georgi, Hodirnau, Victor-Valentin, Wan, William, Schur, Florian K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755917/
https://www.ncbi.nlm.nih.gov/pubmed/33353942
http://dx.doi.org/10.1038/s41467-020-20286-x