Synthetic Artificial Long Non-coding RNA Shows Higher Efficiency in Specific Malignant Phenotype Inhibition Compared to the CRISPR/Cas Systems

Objective: Both oncogenic transcription factors (TFs) and microRNAs (miRNAs) play an important regulator in human cancer by transcriptional and post-transcriptional regulation, respectively. These phenomena raise questions about the ability of artificial device to regulate miRNAs and TFs simultaneou...

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Detalles Bibliográficos
Autores principales: Yao, Lin, Zhang, Quan, Li, Aolin, Ma, Binglei, Zhang, Zhenan, Liu, Jun, Liang, Lei, Zhu, Shiyu, Gan, Ying, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755931/
https://www.ncbi.nlm.nih.gov/pubmed/33363214
http://dx.doi.org/10.3389/fmolb.2020.617600

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